Anne Rice's Interview with the Vampire, or simply Interview with the Vampire, is an American gothic horror television series developed by Rolin Jones for AMC, based on The Vampire Chronicles by Anne Rice, named after the first book. Starring Jacob Anderson as Louis de Pointe du Lac and Sam Reid as Lestat de Lioncourt, it begins with the vampire Louis recounting his past and tumultuous relationship with the vampire Lestat.

The series embraces the queer elements of Rice's work, which are only insinuated in the 1994 film adaptation, and deals with themes such as race and abuse. It is the first series set in the Immortal Universe, a shared universe based on Rice's novels. A series order was made in June 2021, after AMC Networks purchased the rights to intellectual property encompassing 18 of Rice's novels in 2020.

The series premiered on October 2, 2022, with the first two seasons covering the events of the novel. The series was renewed for a third season in June 2024 and is slated to return in 2026 with the title Anne Rice's The Vampire Lestat, covering the second book in the novel series. The series received positive reviews, with praise for its writing, costumes, soundtrack, production design, lead performances and their chemistry. It has received nominations at the Critics' Choice Television Awards and GLAAD Media Awards among others.

Interview with the Vampire centers on the life story of vampire Louis de Pointe du Lac, as told to veteran journalist Daniel Molloy, to whom he previously gave an unpublished interview in 1973. An affluent black man in the 1910s New Orleans, Louis is romanced and later made a vampire by the charismatic Lestat de Lioncourt. But Louis struggles with his humanity, and the introduction of Lestat's newest fledgling, the teenage vampire Claudia, only strains their relationship further. In the present, Daniel begins to doubt the veracity of Louis' story, noting differences from the earlier version.

Additionally, Steven G. Norfleet guest starred as Paul de Pointe du Lac, Louis's troubled brother, while Damon Daunno guest starred as Bruce or Killer, a lone vampire Claudia meets during her travels, and Luke Brandon Field guest starred as Young Daniel Molloy. In season two, Blake Ritson and Stephanie Hayes guest starred as Morgan Ward and Emilia, a couple of refugees Louis and Claudia meet in Romania, while Joseph Potter guest-starred as Nicolas de Lenfent, Lestat's former friend and lover, and Justin Kirk guest-starred as Raglan James, a member of the Talamasca.

A new franchise adaptation of Anne Rice's The Vampire Chronicles was initially in development as a film series at Universal Pictures and Imagine Entertainment. The novel series had previously been adapted into Interview with the Vampire, starring Tom Cruise and Brad Pitt, in 1994 and the less commercially successful 2002 sequel, Queen of the Damned. Rice's son, Christopher Rice, had adapted the screenplay, and Alex Kurtzman and Roberto Orci were set as producers. The project paused until November 26, 2016, when Anne Rice had regained the rights to the franchise with the intention to develop the novels into a television series, where she and her son would serve as executive producers. Upon this announcement, Rice stated, "A television series of the highest quality is now my dream for Lestat, Louis, Armand, Marius, and the entire tribe. Though we had the pleasure of working with many fine people in connection with this plan, it did not work out. It is, more than ever, abundantly clear that television is where the vampires belong."

On April 28, 2017, it was announced that Paramount Television Studios and Anonymous Content had optioned the rights after a competitive month-long bidding war. Christopher Rice was attached to rewrite the screenplay, with Anonymous Content's David Kanter and Steve Golin joining as executive producers. On January 11, 2018, Bryan Fuller became the showrunner, but quit later that month to not interfere with what the Rices were planning. In a competitive situation, Hulu put the project in development on July 17, 2018, with Dee Johnson replacing Fuller as showrunner on February 19, 2019. It was later announced on December 19, 2019, that Hulu had decided not to move forward with the project, with Rice adding her trilogy Lives of the Mayfair Witches, the rights to which were still owned by Warner Bros. Pictures, to the larger, complete rights package. Paramount Television was in a position to regain the rights to the novels as it was reported the studio was among the four bidders seeking the property.

On May 13, 2020, it was announced that AMC Networks had purchased the rights to the intellectual property encompassing 18 novels and the possibility to develop feature films and television series from the deal. On June 24, 2021, AMC gave an adaptation of the first novel in the series, Interview with the Vampire, a series order consisting of eight episodes, with the series scheduled to premiere in 2022. Rolin Jones was attached as creator, showrunner, and writer. Mark Johnson was named executive producer alongside Jones under their overall deals with AMC Studios to oversee the universe for AMC, with Anne and Christopher Rice set as non-writing executive producers. On July 19, 2021, it was announced that Alan Taylor was attached as an executive producer and to direct the first two episodes of the first season. On September 28, 2022, ahead of the series premiere, AMC renewed Interview with the Vampire for a second season which will cover the second half of the novel, bringing the series to a total of fifteen episodes.