A machine gun (MG) is a fully automatic and rifled firearm designed for sustained direct fire. Automatic firearms of 20 mm (0.79 in) caliber or more are classified as autocannons rather than machine guns.

As a class of military kinetic projectile weapons, machine guns are designed to be mainly used as infantry support weapons and generally used when attached to a bipod or tripod, a fixed mount or a heavy weapons platform for stability against recoil. Many machine guns also use belt feeding and open bolt operation, features not normally found on other infantry firearms.

Machine guns can be further categorized as light machine guns, medium machine guns, heavy machine guns, general-purpose machine guns, and squad automatic weapons.

Unlike semi-automatic firearms, which require one trigger pull per round fired, a machine gun is designed to continue firing for as long as the trigger is held down. Nowadays, the term is restricted to relatively heavy crew-served weapons, able to provide continuous or frequent bursts of automatic fire for as long as ammunition feeding is replete. Machine guns are used against infantry, low-flying aircraft, small boats and lightly/unarmored land vehicles, and can provide suppressive fire (either directly or indirectly) or enforce area denial over a sector of land with grazing fire. They are commonly mounted on fast attack vehicles such as technicals to provide heavy mobile firepower, armored vehicles such as tanks for engaging targets too small to justify the use of the primary weaponry or too fast to effectively engage with it, and on aircraft as defensive armament or for strafing ground targets, though on fighter aircraft true machine guns have mostly been supplanted by large-caliber rotary guns.

Some machine guns have in practice sustained fire almost continuously for hours; other automatic weapons overheat after less than a minute of use. Because they become very hot, the great majority of designs fire from an open bolt, to permit air cooling from the breech between bursts. They also usually have either a barrel cooling system, slow-heating heavyweight barrel, or removable barrels which allow a hot barrel to be replaced.

Although subdivided into "light", "medium", "heavy" or "general-purpose", even the lightest machine guns tend to be substantially larger and heavier than standard infantry arms. Medium and heavy machine guns are either mounted on a tripod or on a vehicle; when carried on foot, the machine gun and associated equipment (tripod, ammunition, spare barrels) require additional crew members.

Light machine guns are designed to provide mobile fire support to a squad and are typically air-cooled weapons fitted with a box magazine or drum and a bipod; they may use full-size rifle rounds, but modern examples often use intermediate rounds. Medium machine guns use full-sized rifle rounds and are designed to be used from fixed positions mounted on a tripod. The term heavy machine gun originated in World War I to describe heavyweight medium machine guns, and persisted into World War II with Japanese Hotchkiss M1914 clones; today, however, it is used to refer to automatic weapons with a caliber of at least 12.7 mm (0.5 in), but less than 20 mm (0.8 in). A general-purpose machine gun is usually a lightweight medium machine gun that can either be used with a bipod and drum in the light machine gun role or a tripod and belt feed in the medium machine gun role.

Machine guns usually have simple iron sights, though the use of optics is becoming more common. A common aiming system for direct fire is to alternate solid ("ball") rounds and tracer ammunition rounds (usually one tracer round for every four ball rounds), so shooters can see the trajectory and "walk" the fire into the target, and direct the fire of other soldiers.