Marchirolo is a comune (municipality) in the Province of Varese in the Italian region Lombardy, located about 60 kilometres (37 mi) northwest of Milan and about 15 kilometres (9 mi) north of Varese. As of 31 December 2004, it had a population of 3,355 and an area of 5.5 square kilometres (2.1 sq mi).

Marchirolo borders the following municipalities: Cadegliano-Viconago, Cuasso al Monte, Cugliate-Fabiasco, Marzio.