Marco Mendicino (Italian: [ˈmarko mendiˈtʃiːno]; born July 28, 1973) is a Canadian lawyer and former politician who served as the 16th chief of staff to the prime minister in 2025. A member of the Liberal Party, he served as the member of Parliament (MP) for Eglinton—Lawrence from 2015 to 2025. He previously served as the minister of immigration, refugees and citizenship from 2019 to 2021 and the minister of public safety from 2021 to 2023.

In a statement issued on January 2, 2025, Mendicino said he would not be running again in the upcoming 2025 federal election, criticizing the Trudeau government for not taking a more pro-Israel stance (such as on the genocide case against Israel). On March 10, 2025, newly elected Prime Minister Mark Carney chose Mendicino as his interim chief of staff; he was succeeded by Marc-André Blanchard in July 2025.

Mendicino was born in the City of Toronto to Italian immigrant parents. His family's names are on two of the tribute plaques on Villa Charities Italian Canadian Immigrant Tribute. He attended St. Michael's Choir School and graduated high school from Michael Power St. Joseph's. Following high school, he received a BA (Honours) in political science at Carleton University and a Juris Doctor (JD) from the University of Windsor Law School. Later in his career he also studied human resources management at York University's Schulich School of Business.

Mendicino worked as a federal prosecutor for ten years, during which time he was involved in the handling of the Toronto 18 terrorism case.

He also worked for the Law Society of Upper Canada, served as the president of the Association of Justice Counsel, and taught as an adjunct professor at Osgoode Hall Law School.

Mendicino was occasional member of the Eglinton—Lawrence Liberal riding executive, and served as legal counsel to provincial Liberal candidate Mike Colle's campaign in 2014.

Mendicino stood for the federal nomination for the 2015 general election. He faced a major battle for the nomination after Conservative MP Eve Adams crossed the floor to join the Liberal Party. With the support of party leader Justin Trudeau, sought the Liberal nomination in Eglinton—Lawrence. Mendicino secured the support of former interim Liberal leader Bob Rae and nearby incumbent MP Judy Sgro. He defeated Adams at the July 26, 2015, nomination meeting by 1,936 to 1,100 votes.

In the general election, Mendicino faced the incumbent Conservative MP Joe Oliver, who was Minister of Finance, as well as a surprise New Democratic Party nominee in former Saskatchewan finance minister Andrew Thomson. Mendicino attacked Thomson as a parachute candidate. Ultimately, Mendicino won the election.