Mariano Comense (Brianzöö: Marian [maˈrjãː]) is a town and comune in the province of Como, Lombardy, Italy. It has c. 23,600 inhabitants and is one of the most important cities of the Brianza. It received the honorary title of city with a presidential decree on February 29, 1996. It is served by Mariano Comense railway station.

Monnet Xenia Sport is an amateur football club based in Mariano Comense It competes in the Prima Categoria, Group B, for the 2024-2025 season. The principal football team of Mariano Comense is Mariano Calcio, which is competing in Eccellenza