Joyner began working for Madame C.J. Walker, a pioneering African American entrepreneur in the beauty industry, in 1916. She was hired as an assistant to Walker and quickly rose through the ranks due to her talent and dedication.

Marjorie was promoted to National Supervisor of Walker's beauty schools, overseeing over 200 schools across the United States. In this role, she trained thousands of women in beauty culture and business skills.

Throughout much of the 20th century, Joyner remained an influential figure within the Walker Manufacturing Company, contributing to its growth and innovation in the hair care industry. She also took on responsibilities such as fundraising and fundraising for other initiatives.

After Madame C.J. Walker's death, Marjorie Joyner continued to serve as an important figure within the company. She took on new leadership roles and guided the company through transitions.

After a long and successful career, Marjorie Joyner retired from Walker Manufacturing Company.