Mary is credited with inventing the tribikos, a three-armed alembic used for distillation. The tribikos allowed for more efficient and controlled heating and collection of distilled substances, marking a significant advancement in alchemical apparatus. This highlights her practical, inventive nature.

The kerotakis, another invention attributed to Mary, was a sophisticated apparatus used for heating substances in a controlled environment, often used in conjunction with metals. The kerotakis's design allowed the alchemist to observe and control the reaction process, essential for specific alchemical transmutations. This demonstrated an understanding of chemical reactions.

Although the exact date is unknown, Mary is often associated with the development of the bain-marie (water bath), a technique for gentle, indirect heating. This method proved invaluable for temperature-sensitive reactions and extractions, and remains an essential laboratory technique to this day. This highlights her important and lasting practical contributions.