A. N. McCallum High School is a public high school in Austin, Texas, United States.

McCallum, the second oldest high school in the Austin Independent School District (formerly known as Austin Public Schools prior to desegregation in 1971), opened in 1953 to relieve growth in north and northwest Austin. It is named after AISD's first high school superintendent, A.N. McCallum.

In 1994, McCallum motioned to make its campus the home of AISD's Fine Arts Academy. Currently, the Fine Arts Academy is open to all students in AISD who wish to attend, given that they are accepted following an admissions process. Current fine arts strands include visual arts, dance, theatre (acting/performance and technical), cinematic arts, voice, and instrumental music (band, orchestra, classical guitar, and collaborative piano). The Fine Arts Academy was recently named the 2015 Grammy Foundation's National Signature School, the lone recipient out of thousands of fine arts high schools in the country. McCallum had previously ranked as a Signature School Finalist in 2005, a decade before winning the highest award possible.

Topping the list of thirteen high schools in the country, McCallum's recognition as the National Signature School earned the music program $5,000 from the Grammy Foundation and the Grammy In The Schools program. As recipient of the Foundation's Gold Award, McCallum High School earned the title of best music program in a public U.S. high school through making outstanding commitments to arts education throughout an academic school year. Student ensembles benefitting directly from this award included concert band, choral ensemble, orchestra, classical guitar ensemble, jazz band, and steel pan ensemble.

Plans for a new high school campus in North Austin began as early as 1947, and were formalized at the Austin School Board meeting on May 9, 1949. At that time, the only (white) high school campus in town was Stephen F. Austin High School, which, prior to expansion, was simply known as "Austin High". With Austin High's population approaching 3000 students, the board perceived the need to expand in order to support the city's post-war population boom. McCallum High School was designed by the architecture firm Page Southerland Page, which was founded by Charles Henry Page, and which also designed several other historic structures in the Austin area. Construction began in March 1951 at a total cost of $1.4M, or $11.88 per square foot, and the school's first classes were held on September 8, 1953. At its opening, initial enrollment was 1,336 students, of which 683 were in grades 9-12, and there were 62 total teaching, administrative and clerical staff.

In 1956 the first African-American student began attending McCallum as part of desegregation; a total of 13 black students attended white high schools in AISD at that time. In 1994, the Fine Arts Academy enrolled 17 students, and now has over 500 students. The Academy gained visibility as its own entity within the high school with a professionally designed logo, creation and maintenance of the Academy website, and increased social media coverage.

In 2004, McCallum High School band performed at a ceremony in which Mayor Will Wynn proclaimed October 25 Mangiasaurus Day.

In 2009, portions of the film Bandslam featuring Vanessa Hudgens and Lisa Kudrow were filmed on the McCallum campus.