Medomsley is a village in County Durham, England. It is about 2 miles (3 km) northeast of the centre of Consett, 1+1⁄2 miles (2 km) south of Hamsterley and 1 mile (2 km) southeast of Ebchester along the B6309. Leadgate lies a further mile to the south east.

Medomsley is about 778 feet (237 m) above sea level, atop a hill overlooking the Derwent Valley. The village has views of the Pennines and the surrounding countryside for miles around.

The Boldon Book of 1183 records Medomsley as Medomesley. The Vita S Godrici, written in 1190, records it as Madmeslei. The placename is derived from Old English and may mean the “middlemost clearing” or “Maethhelm’s clearing”.

The Church of England parish church of St Mary Magdalene is a sandstone building completed in the 13th century. In 1878 it was restored to designs by the architects HJ Austin, RJ Johnson and WS Hicks, who added a new roof, chancel screen (designed by Hicks) and north aisle. It is a Grade I listed building.

Medomsley's church served many inhabitants of Shotley Bridge for baptisms, marriages and burials until the creation of Shotley Bridge parish in the 19th century. The sword-makers of Shotley Bridge were frequent visitors of the church, and the parish registers record many of these events.^{[citation needed]}

The antiquarian and physician Christopher Hunter (1675–1757) was born at Medomsley Hall.

There were two collieries near the village: Medomsley Colliery southwest of the village and Derwent Colliery immediately to the north. Medomsley Colliery was opened in 1839. It was also known as the Busty pit, and is not to be confused with South Medomsley Colliery near Annfield Plain. Derwent Colliery was opened in 1856.

Both pits were opened by Edward Richardson and Co. The Consett Iron Company took them over in the 1860s. They were nationalised in 1947.