Mersey Beat was a music publication in Liverpool, England in the early 1960s. It was founded by Bill Harry, who was one of John Lennon's classmates at Liverpool Art College. The paper carried news about all the local Liverpool bands, and stars who came to town to perform.

The Beatles had a close association with Mersey Beat, which carried many exclusive stories and photos of them. It also published several of Lennon's early writings, including a history of the band, and occasional comical classified advertisements by him as space filler.

A fellow student, John Ashcroft, introduced Harry to rock 'n' roll records, and the members of Rory Storm & The Hurricanes and Cass & The Cassanovas. Harry carried notebooks with him, collecting information about the local groups, once writing to The Daily Mail: "Liverpool is like New Orleans at the turn of the century, but with rock 'n' roll instead of jazz". He also wrote to The Liverpool Echo about the emerging Liverpool music scene, but neither paper was interested in stories about music that was popular with teenagers. The classified ads in The Liverpool Echo for local groups were always under the heading of Jazz, but the paper refused to change this policy, despite pleas from the promoters and groups who actually paid for them. Harry planned to produce a jazz newspaper called Storyville/52nd Street and contacted Sam Leach, the owner of a club called Storyville. Leach promised to fund the newspaper, but failed to turn up for three meetings with Harry, leaving him no other option but to find another investor. Harry thought starting a fortnightly newspaper covering Liverpool's rock 'n' roll music scene would be more successful, and would differ from national music newspapers such as the New Musical Express and the Melody Maker, which only wrote articles about current chart hits and artists.

Photographer Dick Matthews, a friend from the Jacaranda, heard about Harry's problems with Leach and introduced Harry to a local civil servant, Jim Anderson, who lent Harry £50. This enabled Harry to found Mersey Beat in 1961. Harry decided to publish the newspaper every two weeks, covering the music scene in Liverpool, Wirral, Birkenhead, New Brighton, Crosby and Southport, as well as Warrington, Widnes and Runcorn. He thought up the name Mersey Beat by thinking about a policeman's 'beat' (the area of duty), which had nothing to do with a musical beat. Harry's fiancé Virginia Sowry gave up her accountancy/comptometer operator job at Woolworth's and worked full-time for two guineas (£2.10/-) a week (also contributing a Mersey Roundabout article), while Harry lived on his Senior City Art Scholarship funding. Matthews photographed groups, while Anderson found a small attic office for £5 a week above David Land's wine merchant's shop at 81a Renshaw Street, Liverpool. Anderson and Matthews helped with the move to the new office, with Anderson providing a desk, chair and an Olivetti typewriter.

Harry asked printer James E. James (who had printed Frank Comments), if he could borrow the printing blocks he used for photos, as they were too expensive for the fledgling company at the time. Harry also borrowed blocks from the Widnes Weekly News, Pantosphinx and local cinemas, but contributed to charities by printing free charity advertisements at the side of the front cover page. After taking Virginia home to Bowring Park in the evening, Harry would often return to the office and work throughout the night, pausing only to go to the Pier Head to buy a cup of tea and a hot pie at four in the morning. Virginia's parents helped the paper during this time, as they paid for classified ads, and arranged for Harry and his future wife's first photographs together.

Splitting the price of the newspaper (three pence), with retailers, Harry arranged for three major wholesalers, W.H. Smith, Blackburn's, and Conlan's, to sell Mersey Beat. Harry personally delivered copies to more than 20 newsagents as well as to local venues and musical instrument and record stores, such as Cramer & Lea, Rushworth & Draper, and Cranes. The paper released its first edition on 6 July 1961, selling out all 5,000 copies. The paper's circulation increased rapidly as Harry started featuring stories about groups in Manchester, Birmingham, Sheffield and Newcastle, with circulation growing to 75,000. As the newspaper's sales rose, it became known as the "Teenagers Bible". Local groups were soon being called "beat groups", and venues started advertising concerts as "Beat Sessions". With circulation rising, the paper's offices were moved downstairs to a larger two-roomed office. The Cavern Club's doorman, Pat (Paddy) Delaney, was employed to deliver copies, a secretary, Pat Finn, was hired, as well as Raymond Kane to promote advertising space,

Harry later said: "The newspapers, television, theatres and radio were all run by people of a different generation who had no idea of what youngsters wanted. For decades they had manipulated and controlled them. Suddenly, there was an awareness of being young, and young people wanted their own styles and their own music, just at the time they were beginning to earn money, which gave them the spending power. Mersey Beat was their voice, it was a paper for them, crammed with photos and information about their own groups, which is why it also began to appeal to youngsters throughout Britain as its coverage extended to other areas." Because of the employment situation in Liverpool at the time, The Daily Worker newspaper denounced the enthusiasm of younger people in Liverpool by saying "The Mersey Sound is the sound of 30,000 people on the dole."

Between 1958 and 1964, the Merseyside area had about 500 different groups, which were constantly forming and breaking up, with an average of about 350 groups playing concerts on a regular basis. In 1961, Harry and The Cavern Club's DJ, Bob Wooler, compiled a list of groups that they had personally heard of, which had almost 300 names. In 1962, Mersey Beat held a poll to find out who was the most popular Merseyside group. When the votes were counted, Rory Storm & The Hurricanes were in first place, but after looking through the postal votes again, Harry noticed that forty votes were all written in green ink, in the same handwriting, and from the same area of Liverpool, so the dubious votes were declared void. This was suspected to have been Storm himself, but Harry had no idea that The Beatles had done exactly the same thing.