Ministry of Sound or Ministry of Sound Group is a multimedia entertainment business based in London with a nightclub, shared workspace and private members' club, worldwide events operation, music publishing business and fitness studio.

James Palumbo is the co-founder and former chairman and CEO of the Group. He handed over the day-to-day running of the business to Lohan Presencer in 2008. In 2018, Presencer became chairman.

Ministry of Sound began as the idea of Justin Berkmann. Inspired by New York's Paradise Garage – which he described as "an amazing club. It had lights, darkness, music, quiet – everything you wanted" As opposed to striking a balance between the typical hallmarks of a live music venue, Ministry of Sound was conceived as an arena purely dedicated to sound. Berkmann stated: "My concept for Ministry was purely this: 100% sound system first, lights second, design third (in that order); the reverse of everyone else's idea." According to him, they spent £500,000 on the club's sound system, and the same amount again on soundproofing the club using magnesite: they wanted to be able to turn the sound system up as loud as possible without disturbing the neighbours, and tested it to a volume of 156 decibels without the sound leaking outside. In addition to drawing inspiration from the Paradise Garage, the club borrowed the idea of using changing set designs from another New York City club, Area, with the first being based around Blade Runner, Berkmann's favourite film.

Berkmann was introduced to James Palumbo, who was working in property finance at the time, by Humphrey Waterhouse to realise the concept. The site, a disused bus garage, is located in Elephant & Castle in Southwark, London. The club opened on 21 September 1991 and has remained in this location since. Having considered "a load of daft names" for the club, including Get Off My Foot and The Ghost and Mrs Chicken, Berkmann came up with Ministry of Sound after walking past the Ministry of Defence Main Building.

With opening sets from American house and garage DJs Larry Levan, David Morales, Roger Sanchez and Tony Humphries, as well as Paul Oakenfold, Ministry of Sound grew as a clubbing venue. According to Berkmann, it managed to empty rival nightclub Tramp for its first six months by drawing its celebrity clientele, before "they stopped coming and it was more about the dance music community". It now attracts around 300,000 clubbers per year and has hosted sets from popular DJs including: Adam Beyer, DJ Harvey, Dixon, Marshmello, Jozeff and Pete Tong. It has won the IDMA 'World's Best Sound System' award four years in a row - every year they ran the category.

The capacity of The Box (the main room) is 600 people, and there are other smaller rooms within the club. There are three weekly club nights: Fridays feature Lock n Load brand The Gallery which are primarily trance music, whilst Saturdays host a number of club nights which are primarily house music. In 2016, these included Defected, Glitterbox, Rinse FM, Hospitality and Together. On Tuesday, the club hosts a student session called Milkshake, established in 2002.^{[citation needed]}

Ministry of Sound's existence has been threatened on a number of occasions by nearby redevelopment in Elephant & Castle. The most notable concerned the redevelopment of Eileen House, a tower block opposite the nightclub's entrance. From 2009 to 2014, Ministry of Sound fought various public campaigns to save the club from the threat of closure. These culminated in a hearing before then-Mayor of London Boris Johnson at City Hall in November 2013. On 19 December 2013, a legal deal was agreed between Ministry of Sound and the developer Oakmayne to enable Eileen House to be redeveloped without jeopardizing the club's future.

In 2016, Ministry of Sound partnered with Dolby Laboratories to bring surround sound Dolby Atmos to the nightclub, a first in the industry. The Box, Ministry of Sound's main room, now boasts a 64-speaker, 22-channel sound system, allowing the artists to control where certain sounds are sent across the space.