Moscow State School 57 (Russian: Пятьдесят седьмая школа) is a public school located in the Khamovniki District of Moscow, Russia. The school was founded in 1877 and is best known for its specialized secondary program in mathematics and its alumni.

In 1877, Karl Masing [ru], a Russian engineer and educator, founded a realschule in Maly Znamensky Lane, which soon became one of the most progressive vocational schools in Russia.

After the October Revolution, the realschule was converted into a boarding school with courses in aesthetic arts and renamed to School 4. It became popular with the Soviet establishment, with top government officials sending their children there.

In 1936, the school was transformed again, converting back to a vocational school and acquiring the number 57 in Moscow's educational system.

In 1968, Nikolay Konstantinov, a Russian educator in mathematics, established specialized math classes at the school. Konstantinov's teaching methodology still is used in these classes to this day and has been shared with other educational centers.

The high school offers specializations in humanities, biology, and mathematics, as well as a general track. In 2008–2013, the school merged with two other schools in different locations of the Khamovniki District of Moscow, in conformity with recent reforms in educational policy.

The school has a total enrollment of over a thousand students, entering first, eighth and ninth grade.

Admission to elementary school is competitive and based on test results of the students previously enrolled in the school's tuition-based mandatory preschool program. In 2015, the admission committee considered over a thousand applicants for 130 positions. By maintaining good standing the students can guarantee their further education in the school's general track middle and high school.