Mounds View High School is a public high school in Arden Hills, Minnesota, enrolling approximately 1,800 students in grades 9-12. Along with Irondale High School, it is one of two high schools operated by Mounds View Public Schools (District 621). Located in a suburban area of the Twin Cities about nine miles north of downtown Minneapolis and St. Paul, its attendance area includes parts of Arden Hills, Shoreview, North Oaks, Roseville, and Vadnais Heights. Since 2014, it has been a member of the Suburban East Conference of the Minnesota State High School League.

U.S. News & World Report named Mounds View High School among the nation's 15 best high schools for exceeding expectations with regard to student performance on reading and math tests, and for preparing students for college. Through the Post Secondary Enrollment Options (PSEO) program, students may take classes at institutions in the Minnesota State Colleges and Universities system. The average ACT score at Mounds View High School is 25.4 (2016), compared to the state average of 21.1, with 99% of the senior class taking the ACT.

The school's Science Olympiad team frequently ranks first in the state and in the top ten nationwide, finishing as high as second place at the 2014 Science Olympiad national tournament and fifth at the 2015 and 2018 tournaments.