Mr Selfridge is a British period drama television series about Harry Gordon Selfridge and his department store, Selfridge & Co, in London, set from 1908 to 1929. It was co-produced by ITV Studios and Masterpiece/WGBH for broadcast on ITV. The series began broadcasting on ITV on 6 January 2013 and 30 March 2016 on PBS in the United States.

In the series, Selfridge has successfully modernized the department store Marshall Field's in Chicago before deciding to open the finest department store in the world in London's Oxford Street. The socialite Lady Mae Loxley is among his first allies. The series depicts a number of historical figures which have interactions with Selfridge or his staff over the following decades, including (among others) the French aviator Louis Blériot, the Russian ballerina Anna Pavlova, the detective fiction writer and spiritualist Arthur Conan Doyle, the Anglo-Irish explorer Ernest Shackleton, and the British monarch Edward VII. By the end of the series in the late 1920s, Selfridge is forced to step down from his leadership position after acquiring the store William Whiteley Limited and unwittingly inheriting its debts to unpaid suppliers.

It was announced on 24 May 2011 that ITV was in discussions with ITV Studios about developing an adaptation of Lindy Woodhead's biography Shopping, Seduction & Mr Selfridge. Andrew Davies was confirmed to be working on the script. Beginning in London in 1908, during a time period when women were enjoying an ever-increasing amount of freedom, it tells the story of Harry Gordon Selfridge, the founder of Selfridges department store and includes members of his family, particularly his wife Rose Selfridge.

It was originally planned to be screened in late 2012, and it is claimed that ITV was forced to postpone airing the drama to January 2013 due to rival BBC airing a similarly themed drama series The Paradise which was broadcast on 25 September 2012.

A set to the north of London was built to house a replica of the 1909 Selfridge's store interior. The exterior of the store was recreated in The Historic Dockyard Chatham, in Kent.

The disused Aldwych tube station was used to film Rose Selfridge travelling on the London Underground and scenes in the first episode.

On 8 February 2013, ITV announced Mr Selfridge had been commissioned for a second series of ten episodes, to start on 19 January 2014. Anthony Byrne, who directed three episodes of series one, returned to direct some of the new episodes. On 22 July 2013, PBS also purchased a second series that aired in 2014 as part of its Masterpiece Classic. The second series is set in 1914 and portrays the consequence of World War I to the store and staff. On 21 February 2014, it was announced that Mr. Selfridge had been renewed for a third series, to air in 2015. On 13 March 2015, ITV announced Mr Selfridge had been commissioned for a new 10-part fourth and final series.

On 11 March 2016, Mr Selfridge aired its final episode after the conclusion of the fourth series and a total of 40 episodes were produced.