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Mycoplasma hominis
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Mycoplasma hominis
Mycoplasma hominis (also known as Metamycoplasma hominis) is a species of bacteria in the genus Mycoplasma. M. hominis has the ability to penetrate the interior of human cells. Along with ureaplasmas, mycoplasmas are the smallest free-living organisms known.
They have no cell wall and therefore do not Gram stain.
Mycoplasma hominis is associated with pelvic inflammatory disease and bacterial vaginosis. It is also associated with male infertility. This species causes a sexually transmitted infection. It is susceptible to the antibiotic clindamycin.
Growth of "fried egg" colonies on glucose agar medium within 24–48 hours is a characteristic of Mycoplasma hominis.[citation needed]
This pathogen may latently infect the chorionic villi tissues of pregnant women, thereby impacting pregnancy outcome.
Mycoplasma hominis is an opportunistic human mycoplasma species residing in the lower urogenital tract. It is a common human urogenital Mycoplasma species that lacks a cell wall. Due to the absence of the cell wall, M. hominis is innately resistant to β-lactams and to all antibiotics which target the cell wall. Additionally, it is the simplest self-replicating microorganism known. This reaps consequences such as a lack of detection by light microscopy, and complex nutritional requirements. Due to the fact that it does not have a cell wall, Mycoplasma hominis does not gram stain although it is surprisingly often described as gram-negative.
The morphology is quite variable and seems to depend, in part, on the age of the culture as the smallest form observed, coming from the elementary body, is 80 nm to 100 nm wide in diameter. Different cell forms have been observed varying from coccoid cells to filaments and irregularly shaped structures with coccoid forms and ring- or disc-shaped cells reigning predominant. Coccal forms of the species are associated with binary fission while fragmentary filaments, and budding cells were also encountered. This fact along with the fact that in different labs, the same strains grew at different rates, leads to the conclusion that cultural conditions have influenced the rate of division and cellular morphology in this species.
The internal components of the much larger cells in the species are also variable. These cells can contain different structures such as ribosome-like granules, nuclear areas of netlike strands, dense cytoplasmic bodies and large vacuoles. These observations indicate multiple modes of reproduction for this organism.
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Mycoplasma hominis
Mycoplasma hominis (also known as Metamycoplasma hominis) is a species of bacteria in the genus Mycoplasma. M. hominis has the ability to penetrate the interior of human cells. Along with ureaplasmas, mycoplasmas are the smallest free-living organisms known.
They have no cell wall and therefore do not Gram stain.
Mycoplasma hominis is associated with pelvic inflammatory disease and bacterial vaginosis. It is also associated with male infertility. This species causes a sexually transmitted infection. It is susceptible to the antibiotic clindamycin.
Growth of "fried egg" colonies on glucose agar medium within 24–48 hours is a characteristic of Mycoplasma hominis.[citation needed]
This pathogen may latently infect the chorionic villi tissues of pregnant women, thereby impacting pregnancy outcome.
Mycoplasma hominis is an opportunistic human mycoplasma species residing in the lower urogenital tract. It is a common human urogenital Mycoplasma species that lacks a cell wall. Due to the absence of the cell wall, M. hominis is innately resistant to β-lactams and to all antibiotics which target the cell wall. Additionally, it is the simplest self-replicating microorganism known. This reaps consequences such as a lack of detection by light microscopy, and complex nutritional requirements. Due to the fact that it does not have a cell wall, Mycoplasma hominis does not gram stain although it is surprisingly often described as gram-negative.
The morphology is quite variable and seems to depend, in part, on the age of the culture as the smallest form observed, coming from the elementary body, is 80 nm to 100 nm wide in diameter. Different cell forms have been observed varying from coccoid cells to filaments and irregularly shaped structures with coccoid forms and ring- or disc-shaped cells reigning predominant. Coccal forms of the species are associated with binary fission while fragmentary filaments, and budding cells were also encountered. This fact along with the fact that in different labs, the same strains grew at different rates, leads to the conclusion that cultural conditions have influenced the rate of division and cellular morphology in this species.
The internal components of the much larger cells in the species are also variable. These cells can contain different structures such as ribosome-like granules, nuclear areas of netlike strands, dense cytoplasmic bodies and large vacuoles. These observations indicate multiple modes of reproduction for this organism.