North Hollywood High School (NHHS) is a public high school in the North Hollywood neighborhood of Los Angeles, California, United States. It is in the San Fernando Valley and enrolls approximately 2,500 students. Several neighborhoods, including most of North Hollywood, Valley Village, Studio City and Sun Valley, send students to it. It is accredited by the Western Association of Schools and Colleges. Its principal is Ricardo Rosales.

As of 2026, North Hollywood High School is in the finishing stages of a "comprehensive modernization" project started in 2017, which included retrofitting Kennedy Hall and Frasher Hall for safety, demolishing Randolph Hall and many portable classrooms, and constructing a new "C" building, a two-story gymnasium with weightrooms and lockers, outdoor basketball courts, a baseball/softball field, a staff parking lot, an improved computer lab/library, a woodshop, an autoshop, a student store, and tennis courts. The agricultural area, farm, garden, and football field were left untouched. In 2026, the new auditorium was opened and named the John Williams Performing Arts Center

Built in 1927, Lankershim High School was named for the town of Lankershim (first called Toluca, now North Hollywood) and its founding family. It opened with only a main building, auditorium, gymnasium and a shop and mechanics building, with 800 students, graduating its first class in 1928. The Board of Education was asked to employ teachers who were already residents of North Hollywood, creating jobs and education opportunities in the area. Lankershim High School was renamed North Hollywood High School in 1929. In 1937, a girls' gymnasium and a second major classroom building, now named Frasher Hall after former principal Roscoe Frasher, were built. In 1950, the third major classroom building, now named Randolph Hall, was built. In the 1950s, many smaller construction projects took place, including the agricultural classrooms, the boys' gymnasium, the home-side bleachers and the instrumental music room. In 1965, the main hall was named the John F. Kennedy Memorial Hall after the president. In 1966, the cafeteria, student store and two shop buildings were built. In 1973, the Amelia Earhart Continuation High School was built on the campus' northeast corner. In the late 1990s, thirteen modular buildings were installed to support an increase in the number of students.

It was in the Los Angeles City High School District until 1961, when it merged into LAUSD.

In 1996, the LAUSD board voted to move NHHS to a year-round schedule, but after more classroom space was found, the board reversed course. Several NHHS parents and community members did not want a year-round schedule since they feared it would negatively impact the Highly Gifted Magnet. According to the 1996 scheduling, magnet students were supposed to get July–May, which would have affected their ability to attend summer programs operated by Ivy League universities. The Zoo magnet students were to get the September–June schedule.

In 2000, Ramón C. Cortines, the LAUSD superintendent, stated that the overcrowding at NHHS was more severe than originally anticipated, and he announced that NHHS was going year-round. This was despite parents and students protesting against the move for several months. From 2000 to 2007, NHHS was a year-round school with three tracks.

In 2006, East Valley High School opened, relieving overcrowding at NHHS. In 2007, the traditional calendar was re-adopted and the students were divided into many Small Learning Communities (SLCs). All but three of these were closed in June 2012.

In 2015, it was announced that NHHS was selected to undergo major renovations, including upgrading buildings and removing portable buildings, to be completed in five years.