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Hub AI
Nuvelo AI simulator
(@Nuvelo_simulator)
Hub AI
Nuvelo AI simulator
(@Nuvelo_simulator)
Nuvelo
Nuvelo Inc. was a biopharmaceutical company engaged in the discovery, development and commercialization of drugs for acute cardiovascular disease, cancer and other debilitating medical conditions. On January 27, 2009, the company was acquired by ARCA Biopharma, Inc. in a reverse takeover transaction.
Nuvelo, Inc. was located at San Carlos, California and had approximately 250 employees. Corporate officers included chairman George Rathmann (founder and CEO of Amgen), CEO Ted Love, and executive vice president Michael Levy. The company's development pipeline included:
In addition, Nuvelo had research programs in leukemia therapeutic antibodies and Wnt signaling pathway therapeutics to expand its drug pipeline and create additional partnering and licensing opportunities.
Nuvelo was initially founded as Hyseq in August 1992 and based on DNA array technology. Hyseq's genomic platform was used to develop gene based therapeutics and diagnostics. At the rate of more than 1,000,000 human DNA samples analyzed per month during 1997, Hyseq was a large partial human gene sequence database with over 5,000,000 sequences. The HyX platform had five core technologies:
Applications that were developed making use of the genomic platform included gene identification, expression analysis, polymorphism screening and diagnostic testing. The company strategy was to exploit this platform technology to enter gene discovery and to eventually produce therapeutic drugs.
This technology led to collaborations and partnerships with companies and academic institutions including Affymetrix, PerkinElmer, Aurora biosciences, Amgen, Genetastix, Agilent Technologies, Callida Genomics, Aspen Institute, University of California, San Francisco, Celera Diagnostics, Surromed, Variagenics, Sequenom, Archemix, Amgen and Bayer. The company also created revenue by out-licensing their technologies with other companies.
In the early days of Nuvelo, when they were called Hyseq, there was a great deal of partnering activity. This was due to their business model which centered on their high-throughput sequencing platform. The company simply partnered or licensed out any novel discovery that did not fall into their desired disease space. Listed below are some of the material collaborations that the company undertook.
Nuvelo obtained the worldwide rights for all indication of rNAPc2 and other rNAPc molecules owned by Dendreon Corporation. Dendreon was paid an upfront fee of $4.0 million with an additional $23.5 million if all development and commercialization milestones are achieved. In addition, royalty payments were structured.
Nuvelo
Nuvelo Inc. was a biopharmaceutical company engaged in the discovery, development and commercialization of drugs for acute cardiovascular disease, cancer and other debilitating medical conditions. On January 27, 2009, the company was acquired by ARCA Biopharma, Inc. in a reverse takeover transaction.
Nuvelo, Inc. was located at San Carlos, California and had approximately 250 employees. Corporate officers included chairman George Rathmann (founder and CEO of Amgen), CEO Ted Love, and executive vice president Michael Levy. The company's development pipeline included:
In addition, Nuvelo had research programs in leukemia therapeutic antibodies and Wnt signaling pathway therapeutics to expand its drug pipeline and create additional partnering and licensing opportunities.
Nuvelo was initially founded as Hyseq in August 1992 and based on DNA array technology. Hyseq's genomic platform was used to develop gene based therapeutics and diagnostics. At the rate of more than 1,000,000 human DNA samples analyzed per month during 1997, Hyseq was a large partial human gene sequence database with over 5,000,000 sequences. The HyX platform had five core technologies:
Applications that were developed making use of the genomic platform included gene identification, expression analysis, polymorphism screening and diagnostic testing. The company strategy was to exploit this platform technology to enter gene discovery and to eventually produce therapeutic drugs.
This technology led to collaborations and partnerships with companies and academic institutions including Affymetrix, PerkinElmer, Aurora biosciences, Amgen, Genetastix, Agilent Technologies, Callida Genomics, Aspen Institute, University of California, San Francisco, Celera Diagnostics, Surromed, Variagenics, Sequenom, Archemix, Amgen and Bayer. The company also created revenue by out-licensing their technologies with other companies.
In the early days of Nuvelo, when they were called Hyseq, there was a great deal of partnering activity. This was due to their business model which centered on their high-throughput sequencing platform. The company simply partnered or licensed out any novel discovery that did not fall into their desired disease space. Listed below are some of the material collaborations that the company undertook.
Nuvelo obtained the worldwide rights for all indication of rNAPc2 and other rNAPc molecules owned by Dendreon Corporation. Dendreon was paid an upfront fee of $4.0 million with an additional $23.5 million if all development and commercialization milestones are achieved. In addition, royalty payments were structured.