Old Crow is a low-priced brand of Kentucky-made straight bourbon whiskey distilled by Suntory Global Spirits, which also produces Jim Beam and several other brands of whiskey. The current Old Crow product uses the same mash bill and yeast as Jim Beam, but is aged for a shorter period of time.

The Old Crow brand has a venerable history as one of Kentucky's earliest bourbons. Old Crow is aged in barrels for a minimum of three years, and in the United States is 80 proof while Old Crow Reserve is aged for a minimum of four years and is 86 proof.

James C. Crow, a Scottish immigrant, started distilling what would become Old Crow in Frankfort, Kentucky, in the 1830s. Reportedly a very skilled distiller, he made whiskey for various employers, which was sold as "Crow" or, as it aged, "Old Crow" – and the brand acquired its reputation from the latter. Crow died in 1856. W.A. Gaines and Company acquired the name and continued to distill whiskey according to his methods, hiring Crow's assistant William F. Mitchell to be the chief distiller. The substantial remaining stock of original Old Crow acquired near-legendary status. After the Civil War the Old Crow logo was changed from a picture of James Crow to the current crow perched atop grains of barley. In 1875, offering drinks from the last available cask reportedly secured the election of Joseph Clay Stiles Blackburn of Kentucky to his first Congressional term. A dispute over ownership of the name "Old Crow" was decided in 1915 in favor of the Gaines company.

Although the whiskey had been at one time the top selling bourbon in the United States, it underwent a swift decline in the second half of the twentieth century. A production error in the amount of "setback" (the portion of spent mash added to a new batch in the sour mash process) negatively impacted the taste of the whiskey, and the distiller's inability or unwillingness to correct it led to many customers switching to other brands. Parent company National Distillers was sold to Jim Beam in 1987. The Old Crow recipe and distillery were abandoned and the product became a three-year-old bourbon based on the Jim Beam mashbill. In 2013 Glenns Creek Distillery started operations in part of the former Old Crow Distillery.

National Distillers brought out the Old Crow Chessmen ceramic decanters in 1969 as an attractive packaging for its 10-year-old 86-proof bourbon. They stand 12–15.5 inches tall, hold a fifth (about 750 ml) of liquor, and the opposing sides were glazed in golden ochre versus a dark green. A deep-pile carpet chessboard measured 45x45 inches. The decanters sold originally for some US$14. A full set would consist of 32 decanters, 16 of which were pawns. The production was limited to some 2,000 pieces, intended for only one Christmas season, and the molds reputedly were destroyed. Today the bourbon contents of these decanters are highly prized.

Many American politicians and military leaders have been associated with Old Crow.

Confederate General Jubal Early was a fan of Old Crow.

Another famous politician who preferred Old Crow was Henry Clay, of Kentucky, who was even featured in Old Crow advertisements.