Owen Cunningham Wilson (born November 18, 1968) is an American actor and screenwriter. He has frequently worked with filmmaker Wes Anderson, with whom he has shared writing and acting credits on the films Bottle Rocket (1996), Rushmore (1998), and The Royal Tenenbaums (2001)—the latter received a nomination for the Academy Award and BAFTA Award for Best Screenplay. He has also appeared in Anderson's The Life Aquatic with Steve Zissou (2004), The Darjeeling Limited (2007), Fantastic Mr. Fox (2009), The Grand Budapest Hotel (2014), and The French Dispatch (2021).

Wilson also starred in the Woody Allen romantic comedy Midnight in Paris (2011) as disenchanted screenwriter Gil Pender, for which he received a Golden Globe Award nomination. In 2014, he appeared in Paul Thomas Anderson's Inherent Vice and Peter Bogdanovich's She's Funny That Way. He made his Marvel Cinematic Universe debut in the Disney+ series Loki (2021–2023) as Mobius M. Mobius.

Wilson is also known as part of the Frat Pack, with whom he has starred in comedic films Meet the Parents (2000), Zoolander (2001), Starsky & Hutch (2004), Wedding Crashers (2005), You, Me and Dupree, Night at the Museum (both 2006), Night at the Museum: Battle of the Smithsonian (2009), How Do You Know (2010), The Internship (2013), and Night at the Museum: Secret of the Tomb (2014). He has collaborated with Jackie Chan on three action comedy films: Shanghai Noon (2000), Shanghai Knights (2003), and Around the World in 80 Days (2004). He is also known for appearing in the family films Marley and Me (2008) and Haunted Mansion (2023). His non-comedic films include Anaconda (1997), Armageddon (1998), The Haunting (1999), Behind Enemy Lines (2001) and No Escape (2015). His voice acting roles include Lightning McQueen in the Cars film series (2006–2017), the titular character in Marmaduke (2010), and Reggie in Free Birds (2013).

Wilson's accolades include an Academy Award nomination and a BAFTA nomination for Best Original Screenplay (for The Royal Tenenbaums), a Golden Globe and two SAG acting nominations (for Midnight in Paris and The Grand Budapest Hotel) and an Independent Spirit Award (for Inherent Vice).

Wilson was born in Dallas, the middle child of three sons of photographer Laura Cunningham Wilson (b. 1939) and Robert Andrew Wilson (1941–2017), an advertising executive and operator of a public television station. His brothers Andrew and Luke are also actors. Wilson's parents are of Irish descent. As a teenager, Wilson broke his nose twice: the first time in a high school fight, and the second time playing football with friends. “You know, probably my nose wouldn’t have been that great even if it hadn’t been broken," Wilson told The Los Angeles Times.

After getting expelled for cheating in geometry, he attended New Mexico Military Institute. He later attended the University of Texas at Austin, where he pursued a Bachelor of Arts degree in English, but did not graduate. While in college, he met and was roommates with Wes Anderson, who became a director and frequent collaborator.

Wilson made his film debut acting in the Wes Anderson short film Bottle Rocket (1994), which was later expanded into the feature-length film Bottle Rocket (1996). Wilson co-wrote the screenplay with Anderson, and acted opposite his brother Luke Wilson. David Hunter of The Hollywood Reporter praised the film, saying, "A marvelous debut film for its director, writer and lead actors, Bottle Rocket is propelled by a fresh approach to the caper genre". That same year, he had a supporting role in the black comedy The Cable Guy (1996), starring Jim Carrey and directed by Ben Stiller, an early admirer of Bottle Rocket. Wilson played Leslie Mann's date in the film. In 1997, he had a role in the adventure thriller Anaconda and executive produced the James L. Brooks comedy As Good as It Gets.

In 1998, Wilson had roles in the science fiction disaster film Armageddon and the independent drama film Permanent Midnight.