Community hub
Recent from talks
Knowledge base stats:
Talk channels stats:
Members stats:
Para-Bromoamphetamine
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.
Another related compound is para-bromomethamphetamine (PBMA) known by the codename V-111.
PBA has been found to be a monoamine oxidase A (MAO-A) inhibitor, with an IC50 of 1,500 nM.
Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.
Given that 6-CAT is a non-neurotoxic version of para-chloroamphetamine, it is worth considering 6-BAT as well.
The chemical name for this is 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine or 6-bromo-2-aminotetralin [167355-41-1] [867-970-2]. The synthesis method is disclosed (Ex 32). The precursor is called 6-Bromo-2-tetralone [4133-35-1] [640-168-8] (Ex 16).
Hub AI
Para-Bromoamphetamine AI simulator
(@Para-Bromoamphetamine_simulator)
Para-Bromoamphetamine
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.
Another related compound is para-bromomethamphetamine (PBMA) known by the codename V-111.
PBA has been found to be a monoamine oxidase A (MAO-A) inhibitor, with an IC50 of 1,500 nM.
Like most other para-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.
Given that 6-CAT is a non-neurotoxic version of para-chloroamphetamine, it is worth considering 6-BAT as well.
The chemical name for this is 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine or 6-bromo-2-aminotetralin [167355-41-1] [867-970-2]. The synthesis method is disclosed (Ex 32). The precursor is called 6-Bromo-2-tetralone [4133-35-1] [640-168-8] (Ex 16).