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Parkinsonism

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Parkinsonism

Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability.

Both hypokinetic features (bradykinesia and akinesia) and hyperkinetic features (cogwheel rigidity and tremors at rest) are displayed in parkinsonism. These are the four motor signs that are found in Parkinson's disease (PD) – after which Parkinsonism is named – and in dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD), and many other conditions.

This set of signs occurs in a wide range of conditions and may have many causes, including neurodegenerative conditions, drugs, toxins, metabolic diseases, and neurological conditions other than Parkinson's disease.

Parkinsonism is a clinical syndrome characterized by the four motor signs that are found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability.

Parkinsonism gait problems can lead to falls and serious physical injuries. Other common signs and symptoms include:

Parkinsonism occurs in many conditions.

Neurodegenerative conditions and Parkinson-plus syndromes that can cause parkinsonism include:

Evidence exists to show a link between exposure to pesticides and herbicides and PD; a two-fold increase in risk was seen with paraquat or maneb/mancozeb exposure.

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