Pedrosillo de los Aires is a village and large municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile-Leon. It is located 32 kilometres (20 mi) from the provincial capital city of Salamanca and has a population of 384 people.
The municipality covers an area of 70 km2 (27 sq mi). It lies 882 metres (2,894 ft) above sea level and the postal code is 37788.