Persquen (French pronunciation: [pɛʁskɛn]; Breton: Persken) is a commune in the Morbihan department of Brittany in north-western France. Inhabitants of Persquen are called in French Persquennois.

Persquen is located south of Guémené-sur-Scorff. The river Scorff forms part of the commune's northern border. Historically, the village belongs to Vannetais and Pays Pourlet.