Poplar River First Nation (Ojibwe: Azaadiwi-ziibing) is an Ojibwa First Nation in Manitoba, Canada. It is named after the Poplar River, which is the main river on which it resides.

Its landbase is the Poplar River 16, an Indian reserve located approximately on the east side of Lake Winnipeg at the mouth of the Poplar River. The largest city nearest this community is Winnipeg, located approximately 400 kilometres (250 mi) to the south.

The Southeast Resource Development Council is the Tribal Council affiliated with this First Nation. Poplar River is part of Treaty 5 Adhesion, signed on 20 September 1875.

Poplar River First Nation is 3,800 acres (1,500 ha). As of 2013, the total population of registered First Nation peoples was 1,543, with 1245 on-reserve, and 298 off-reserve. The primary language spoken is Ojibwe, with some blending of the Cree dialect also known as Oji-Cree. The majority of surnames are Bruce, Franklin, and Berens.

There is an additional population consisting of Métis and non-status First Nations residing in the community, previously having a neighbouring Métis settlement, but it was abandoned.

The community has no municipality, district, or any other town associated or connected with it.

The two main religions practiced in Poplar River are Roman Catholic and Pentecostal.

The town itself is embedded along the main Poplar River with the primary township located on an atoll of land between Poplar River and Franklin River. The majority of the population resides along these two rivers, including three habitable islands located within the main Poplar River. Gravel highways exist throughout all of the community and bridges cross both rivers to connect all areas of the community. There are no paved concrete or asphalt roads or sidewalks.