Prekmurje (Slovene pronunciation: [pɾɛkˈmúːɾjɛ] also [ˈpɾeːkmuɾjɛ] ^ⓘ; Prekmurje Slovene: Prèkmürsko or Prèkmüre; Hungarian: Muravidék) is a geographically, linguistically, culturally, and ethnically defined region of Slovenia, settled by Slovenes and a Hungarian minority, lying between the Mur River in Slovenia and the Rába Valley (the watershed of the Rába; Slovene: Porabje) in the westernmost part of Hungary. It covers an area of 938 square kilometers (362 sq mi) and has a population of 78,000 people. Its largest town and urban center is Murska Sobota, the other urban center being Lendava.

It is named after the Mur River, which separates it from the rest of Slovenia. The name Prekmurje literally means 'area beyond the Mur' (prek 'beyond, on the other side' + Mura 'Mur River' + je, a collective suffix). In Hungarian, the region is known as Muravidék, and in German as Übermurgebiet.

The name Prekmurje was introduced in the twentieth century, although it is derived from an older term. Before 1919, the Slovenian-inhabited lands of Vas County in the Kingdom of Hungary and Austria-Hungary were known as the Slovene March or "Vendic March" (in Slovenian: Slovenska krajina, in Hungarian: Vendvidék). The part of modern Prekmurje that belonged to Zala County (the area between Lendava, Kobilje and Beltinci) was not considered to be a part of the Slovenian March. Until the early 19th century, this region of the Zala County belonged ecclesiastically to the Archdiocese of Zagreb and in the legal documents of the Archdiocese it was called as "Transmurania" or "Prekmurje", that is the "territory on the other side of the Mur River". After 1919, this name was reintroduced, now for administrative purposes, by the new Yugoslav administration. It, however, did not gain much popularity among the locals. The name "Slovenian March" was still used by the local inhabitants until the mid-1920s, but was gradually replaced by the term "March of the Mur" (Slovenian: Murska krajina). The current Hungarian name for Prekmurje, Muravidék, dates from the interwar period and is a translation of the Slovenian Murska krajina. From the mid-1930s onward, the name Prekmurje became widely used in the press and eventually became the most common name for the region. After World War II, this name replaced all previous designations.

Nowadays, the older term Vendvidék still exists in Hungarian, but it is used only for the small settlement area of Hungarian Slovenes between Szentgotthárd and the Slovenian border that remained part of Hungary after 1919.

The region is divided into three geographical subregions: the hilly area to the north of Murska Sobota, known as Goričko (literally, 'the uplands'); the eastern flatlands along the Mur River, known as Ravensko (literally, 'the flatlands'), and the western lowlands around Lendava, known as Dolinsko (literally, 'the lowlands'). Northeast of Lendava, there is a small hilly sub-region, known as the Lendava Hills (Lendavske gorice).

The administrative and commercial seat of the region is the town of Murska Sobota. The only other major town is Lendava. Other significant rural centres are Beltinci, Turnišče, Dobrovnik, and Črenšovci.

The majority of the inhabitants of the region are ethnic Slovenes. There are also sizable Hungarian and Romani minorities in the region.

In 1921, the total population of the area numbered 92,295, including 74,199 Slovene speakers, 14,065 Hungarian speakers, and 2,540 German speakers. Since then, the number of Hungarian speakers has been falling slowly but steadily. The German-speaking community, which used to be concentrated in three villages near the Austrian border and in Murska Sobota, was either expelled from the area or assimilated after World War II.