Pseudoscience consists of statements, beliefs, or practices that claim to be both scientific and factual but are incompatible with the scientific method. Pseudoscience is often characterized by contradictory, exaggerated or unfalsifiable claims; reliance on confirmation bias rather than rigorous attempts at refutation; lack of openness to evaluation by other experts; absence of systematic practices when developing hypotheses; and continued adherence long after the pseudoscientific hypotheses have been experimentally discredited. It is not the same as junk science.

The demarcation between science and pseudoscience has scientific, philosophical, and political implications. Philosophers debate the nature of science and the general criteria for drawing the line between scientific theories and pseudoscientific beliefs, but there is widespread agreement "that creationism, astrology, homeopathy, Kirlian photography, dowsing, ufology, ancient astronaut theory, Holocaust denialism, Velikovskian catastrophism, and climate change denialism are pseudosciences." There are implications for health care, the use of expert testimony, and weighing environmental policies. Recent empirical research has shown that individuals who indulge in pseudoscientific beliefs generally show lower evidential criteria, meaning they often require significantly less evidence before coming to conclusions. This can be coined as a 'jump-to-conclusions' bias that can increase the spread of pseudoscientific beliefs. Addressing pseudoscience is part of science education and developing scientific literacy.

Pseudoscience can have dangerous effects. For example, pseudoscientific anti-vaccine activism and promotion of homeopathic remedies as alternative disease treatments can result in people forgoing important medical treatments with demonstrable health benefits, leading to ill-health and deaths. Furthermore, people who refuse legitimate medical treatments for contagious diseases may put others at risk. Pseudoscientific theories about racial and ethnic classifications have led to racism and genocide.

The term pseudoscience is often considered pejorative, particularly by its purveyors, because it suggests something is being presented as science inaccurately or even deceptively. Therefore, practitioners and advocates of pseudoscience frequently dispute the characterization.

The word pseudoscience is derived from the Greek root pseudo meaning "false" and the English word science, from the Latin word scientia, meaning "knowledge". Although the term has been in use since at least the late 18th century (e.g., in 1796 by James Pettit Andrews in reference to alchemy), the concept of pseudoscience as distinct from real or proper science seems to have become more widespread during the mid-19th century. Among the earliest uses of "pseudo-science" was in an 1844 article in the Northern Journal of Medicine, issue 387:

That opposite kind of innovation which pronounces what has been recognized as a branch of science, to have been a pseudo-science, composed merely of so-called facts, connected together by misapprehensions under the disguise of principles.

An earlier use of the term was in 1843 by the French physiologist François Magendie, that refers to phrenology as "a pseudo-science of the present day". During the 20th century, the word was used pejoratively to describe explanations of phenomena which were claimed to be scientific, but which were not in fact supported by reliable experimental evidence.

From time to time, however, the usage of the word occurred in a more formal, technical manner in response to a perceived threat to individual and institutional security in a social and cultural setting.