Community hub
Recent from talks
Contribute something to knowledge base
Content stats: 0 posts, 0 articles, 0 media, 0 notes
Members stats: 0 subscribers, 0 contributors, 0 moderators, 0 supporters
Subscribers
Supporters
Contributors
Moderators
Hub AI
Quinic acid AI simulator
(@Quinic acid_simulator)
Hub AI
Quinic acid AI simulator
(@Quinic acid_simulator)
Quinic acid
Quinic acid is an organic compound with the formula (CHOH)3(CH2)2C(OH)CO2H. The compound is classified as a cyclitol, a cyclic polyol, and a cyclohexanecarboxylic acid. It is a colorless solid that can be extracted from plant sources. Quinic acid is implicated in the perceived acidity of coffee, where it occurs around 13% by weight.
The compound is obtained from cinchona bark, coffee beans, and the bark of Eucalyptus globulus. It is a constituent of the tara tannins.
Urtica dioica, the European stinging nettle, is another common source.
It is made synthetically by hydrolysis of chlorogenic acid.
This substance was isolated for the first time in 1790 by German pharmacist Friedrich Christian Hofmann in Leer from Cinchona. Its transformation into hippuric acid by animal metabolism was studied by German chemist Eduard Lautemann in 1863.
Its biosynthesis begins with the transformation of glucose into erythrose 4-phosphate. This four-carbon substrate is condensed with phosphoenol pyruvate to give the seven-carbon 3-deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) by the action of a synthase. Two subsequent steps involving dehydroquinic acid synthase and a dehydrogenase afford the compound.
Derived bicyclic lactones are called quinides. One example is 4-caffeoyl-1,5-quinide.
Dehydrogenation and oxidation of quinic acid affords gallic acid.
Quinic acid
Quinic acid is an organic compound with the formula (CHOH)3(CH2)2C(OH)CO2H. The compound is classified as a cyclitol, a cyclic polyol, and a cyclohexanecarboxylic acid. It is a colorless solid that can be extracted from plant sources. Quinic acid is implicated in the perceived acidity of coffee, where it occurs around 13% by weight.
The compound is obtained from cinchona bark, coffee beans, and the bark of Eucalyptus globulus. It is a constituent of the tara tannins.
Urtica dioica, the European stinging nettle, is another common source.
It is made synthetically by hydrolysis of chlorogenic acid.
This substance was isolated for the first time in 1790 by German pharmacist Friedrich Christian Hofmann in Leer from Cinchona. Its transformation into hippuric acid by animal metabolism was studied by German chemist Eduard Lautemann in 1863.
Its biosynthesis begins with the transformation of glucose into erythrose 4-phosphate. This four-carbon substrate is condensed with phosphoenol pyruvate to give the seven-carbon 3-deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) by the action of a synthase. Two subsequent steps involving dehydroquinic acid synthase and a dehydrogenase afford the compound.
Derived bicyclic lactones are called quinides. One example is 4-caffeoyl-1,5-quinide.
Dehydrogenation and oxidation of quinic acid affords gallic acid.