Régusse (French pronunciation: [ʁeɡys]; Occitan: Regussa) is a commune in the Var department in the Provence-Alpes-Côte d'Azur region in southeastern France.

Régusse has a hot-summer Mediterranean climate (Köppen climate classification Csa). The average annual temperature in Régusse is 13.5 °C (56.3 °F). The average annual rainfall is 717.9 mm (28.26 in) with November as the wettest month. The temperatures are highest on average in July, at around 22.8 °C (73.0 °F), and lowest in January, at around 5.5 °C (41.9 °F). The highest temperature ever recorded in Régusse was 40.9 °C (105.6 °F) on 28 June 2019; the coldest temperature ever recorded was −10.3 °C (13.5 °F) on 13 February 2012.