Weisz starred in 'The Constant Gardener', a political thriller directed by Fernando Meirelles. Her performance as Tessa Quayle earned her critical acclaim and numerous awards, including an Academy Award and a Golden Globe.

Weisz starred in 'The Fountain', a visually stunning and ambitious film directed by Darren Aronofsky. She played multiple roles in different time periods, showcasing her versatility as an actress.

Weisz starred as Hypatia of Alexandria in 'Agora', a historical drama directed by Alejandro Amenábar. Her portrayal of the philosopher and astronomer earned her critical praise.

Weisz starred in 'The Deep Blue Sea', a romantic drama directed by Terence Davies. Her performance as Hester Collyer was highly acclaimed.

Weisz starred in 'The Lobster', a surreal and darkly comedic film directed by Yorgos Lanthimos. Her performance was praised for its subtlety and emotional depth.

Weisz starred in 'My Cousin Rachel', a mystery drama based on the novel by Daphne du Maurier. Her portrayal of the enigmatic Rachel earned her positive reviews.

Weisz starred in 'The Favourite', a historical drama directed by Yorgos Lanthimos. Her performance as Sarah Churchill, Duchess of Marlborough, earned her numerous awards and nominations, including a BAFTA Award and an Academy Award nomination.

Weisz plays Melina Vostokoff in the Marvel Cinematic Universe film Black Widow. She reprised the role in a cameo appearance in the television series Hawkeye (2021).