Rachel Weisz made her professional stage debut in Noël Coward's 'Design for Living' at the Gielgud Theatre. This early role helped establish her presence in the London theatre scene.

She appeared in Tennessee Williams' 'Suddenly Last Summer' at the Comedy Theatre, showcasing her ability to handle complex and emotionally demanding roles.

Weisz starred as Blanche DuBois in Tennessee Williams' 'A Streetcar Named Desire' at the Donmar Warehouse, directed by Rob Ashford. Her performance was highly anticipated and critically acclaimed.

Weisz starred in a Broadway revival of Harold Pinter's 'Betrayal', alongside her husband Daniel Craig and Rafe Spall. The production received positive reviews and was a commercial success.