Renanolone (INN; also known as 11-ketopregnanolone or 5β-pregnan-3α-ol-11,20-dione) is a synthetic^{[citation needed]} neuroactive steroid which is described as a general anesthetic, but was never introduced for clinical use. Its isomers, alfaxolone and alfadolone, are also general anesthetics, and are known to act as positive allosteric modulators of the GABA_A receptor, a property which is likely the case for renanolone as well.