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Robinetin
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| Names | |
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| IUPAC name
3,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
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| Other names
Norkanugin; 5-Hydroxyfisetin
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.007.009 |
| EC Number |
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| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C15H10O7 | |
| Molar mass | 302.238 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Robinetin is an organic compound in the flavone group with the molecular formula C15H10O7. Chemically, it is a flavone with 5 hydroxy groups. Its name originates from the botanical name of the genus Robinia. [1]
Natural role
[edit]It has a role as a plant metabolite and is a pentahydroxyflavone and a 7-hydroxyflavonol.[2] Robinetin is one of the basic chemical extracts of the species black locust, Robinia pseudoacacia and its wood, imparting a high biological resistance against several pathogens (fungi, insects).[3]
As flavonoid, robinetin has also been isolated from the heartwood of the African species, Millettia stuhlmannii.[4]
In plant systems, robinetin as flavonoids in general, help in combating oxidative stress and act as growth regulators.[citation needed]
Research
[edit]Recent research has focused on the health aspects of flavonoids for humans, particularly that of robinetin. It has been shown to possess a certain antioxidative activity, free radical scavenging capacity, coronary heart disease prevention, hepatoprotective, anti-inflammatory, and anticancer activities.[5]
Robinetin also can inhibit lipid peroxidation and protein glycosylation.[citation needed]
References
[edit]- ^ Charlesworth, Edward H.; Robinson, Robert (1933). "73. Anthoxanthins. Part XIII. Synthesis of a colouring matter of Robinia pseudacacia". Journal of the Chemical Society (Resumed): 268. doi:10.1039/JR9330000268.
- ^ "Robinetin". PubChem. Retrieved 2024-08-30.
- ^ "Springer Handbook of Wood Science and Technology (Chapter 3. Wood Biology)". Springer Handbooks. Cham: Springer International Publishing. 2023. p. 107. doi:10.1007/978-3-030-81315-4. ISBN 978-3-030-81314-7. ISSN 2522-8692. S2CID 257902863.
- ^ ILDIS, International Legume Database and Information Service; CHCD, Chapman & Hall Chemical Database (1994). F.A. Bisby; J. Buckingham; J.B. Harborne (eds.). Phytochemical dictionary of the Leguminosae. compiler, I.W. Southon; chemical data, Chapman & Hall Chemical Database; phytochemical database, R.J. White; botanical data, J.L. Zarucchi (1st ed.). London: Chapman & Hall. ISBN 0412397706.
- ^ Kumar, Shashank; Pandey, Abhay K. (2013). "Chemistry and Biological Activities of Flavonoids: An Overview". The Scientific World Journal. 2013 (1). doi:10.1155/2013/162750. ISSN 2356-6140. PMC 3891543. PMID 24470791.
External links
[edit]Flavones and their conjugates | |||||||||||||
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| Aglycones |
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| Glycosides |
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| Acetylated | |||||||||||||
| Sulfated glycosides | Theograndin I and II | ||||||||||||
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