Sean "Hollywood" Hamilton is an American radio personality. On November 8, 2019, he was inducted into the National Radio Hall of Fame. He can be heard weekday mornings hosting the "Hollywood Hamilton Show & The KTU Morning Crew" on WKTU in New York City. On October 5, 2018, iHeartMedia announced a new long-term agreement with Hamilton. Robert Pittman, chairman and CEO of iHeartMedia Inc., stated, "Hollywood Hamilton is one of the most loved, respected and recognized voices and names in radio, his unparalleled ability to connect with both listeners and music's biggest artists is a true representation of what makes radio the most powerful medium in the U.S."

Hamilton was born and raised in both Las Vegas and Reno, Nevada. Both his parents were in show business; his father, Al, was the entertainment director for major Nevada hotels and casinos, and also a comedian who performed in those establishments. Hamilton's mother, April Ames, was a singer for Harry James, Sam Donahue, Buddy Rich, and others during the "big band" era. She made appearances on Johnny Carson and George Gobel television shows. Later, during the 1970s, she performed on the Nevada casino circuit with her own band, April Ames and The Dames. Hamilton got the nickname "Hollywood" when he was nine years old. While sitting backstage watching his father's Las Vegas show wearing a suit and bow tie, one of his father's showgirls passed by, stopped, and called him "Little Hollywood".

While still in high school, Hamilton landed his first job in commercial radio after gaining recognition from an illegal pirate radio station, broadcasting from a walk-in closet in his parents' home in Reno, Nevada. After weeks of complaints from local commercial radio stations, the Federal Communications Commission issued a formal cease and desist. It wasn't until then, that Hamilton's parents even knew of such an operation.

In 1990 actor Christian Slater studied the role of playing a DJ for the motion picture Pump Up the Volume under the tutelage of then friend Hamilton. Because Sean Hamilton's start in radio was very similar to the storyline in the movie, Christian's Mother Mary Jo Slater had personally asked Sean if he'd work with Christian on and off the air while working at KIISFM in Los Angeles.

In 1996, Clear Channel convinced Hamilton to relocate back to New York City to host a show for their WKTU evening slot. Hamilton brought a sidekick/comedian along by the name of Goumba Johnny, their chemistry earned them top ratings consistently for two years. Because of their overwhelming success, in September 2006 Clear Channel decided to promote the duo to WKTU's afternoon drive.

In December 2010, with the departure of sidekick Goumba Johnny, Hamilton started hosting the afternoon drive-time show solo. Since then his show became not only the highest rated afternoon show in the New York metro area but currently also holds the highest rated share for all radio stations in New York. (8.2 share 25–54 demographic, according to the Arbitron PPM/Summer rating system).

In 1996, Hamilton was asked to host the annual Easter Egg Roll at the White House with President Bill Clinton and first Lady Hillary Clinton in Washington, D.C.

On September 2, 2015, WKTU announced that Sean ‘Hollywood’ Hamilton had signed a new three-year deal to extend his contract through 2018. In their press release it stated that Hamilton's show is currently rated the No.1 afternoon show by Arbitron's Portable People Meter (PPM) with adults ages 25–54. It goes on to mention his show features a segment called War of the Roses, weekdays at 5:40 p.m., helping KTU's 5:00 p.m. hour become the most listened to hour in New York City radio.