Brin has expressed interest in the technological singularity and the potential for artificial intelligence to transform humanity. He has supported research and development in areas such as robotics and AI.

Driven by a genetic predisposition, Brin has dedicated significant resources to Parkinson's disease research. He has funded studies aimed at identifying biomarkers, developing new treatments, and understanding the genetic basis of the disease.

Brin has shown interest in airships and has reportedly invested in the development of high-altitude platforms for various applications, including humanitarian aid and internet access in remote areas.

Brin invested in space tourism company Space Adventures, showing his interest in space exploration and the potential for commercial space travel.

Brin has supported initiatives focused on renewable energy and environmental sustainability. He has invested in companies and projects aimed at developing clean energy technologies and reducing carbon emissions.