Shenzhou 15 (Chinese: 神舟十五号; pinyin: Shénzhōu Shíwǔ-hào; lit. 'Divine Boat Number 15') was a Chinese spaceflight to the Tiangong space station, launched on 29 November 2022. It carried three People's Liberation Army Astronaut Corps (PLAAC) taikonauts on board a Shenzhou spacecraft. The mission was the tenth crewed Chinese spaceflight and the fifteenth flight overall of the Shenzhou program.

Shenzhou 15 was the fourth spaceflight to the Tiangong space station, and the third with a standard mission duration of approximately six months. It was also the first mission to the station following its initial completion, with the launch and docking of the Wentian and Mengtian modules in July and October 2022 respectively.

Prior to launch, the Shenzhou 15 spacecraft was maintained in a state of near-readiness if needed as a lifeboat for the Shenzhou 14 crew.

The crew of Shenzhou 15 was announced on 28 November 2022.

The flight launched from Jiuquan Satellite Launch Center on 29 November 2022 at 15:08 UTC, following the launch of Tianzhou 5 and near the end of the Shenzhou 14 mission. Just over 6.5 hours after launch, the spacecraft docked with the Tianhe core module's forward docking port.

The crew entered the station at 23:33 UTC on 29 November, and were greeted by the crew of Shenzhou 14. This marked the first Chinese crew handover in space, and set a new record for total taikonauts in space, at six. There was a five-day overlap between Shenzhou 15 and the previous mission before Shenzhou 14's departure on 4 December.

During the mission, the Shenzhou 16 spacecraft remained on standby to serve as an emergency rescue vehicle.

The Shenzhou 15 crew carried out four spacewalks, worked on payloads both inside and outside the station, and carried out other scientific work during the six-month mission. During Shenzhou 15's stay aboard Tiangong, the Tianzhou 6 cargo spacecraft arrived and docked with the station.