"South Side Rules" is the tenth episode of the fifth season of the American television comedy drama Shameless, an adaptation of the British series of the same name. It is the 58th overall episode of the series and was written by supervising producer Sheila Callaghan and directed by Michael Uppendahl. It originally aired on Showtime on March 22, 2015.

The series is set on the South Side of Chicago, Illinois, and depicts the poor, dysfunctional family of Frank Gallagher, a neglectful single father of six: Fiona, Phillip, Ian, Debbie, Carl, and Liam. He spends his days drunk, high, or in search of money, while his children need to learn to take care of themselves. In the episode, Frank tries to be part of Bianca's life, while Fiona hangs out with Sean after Gus does not show up for a date.

According to Nielsen Media Research, the episode was seen by an estimated 1.67 million household viewers and gained a 0.7 ratings share among adults aged 18–49. The episode received critical acclaim, with praise towards the emotional tone and ending, although some critics commented negatively of Sammi's character development.

Frank (William H. Macy) tries to help Bianca (Bojana Novakovic) with her life, but she instead asks him to leave her house. While watering the plants at his apartment, Fiona (Emmy Rossum) calls Gus (Steve Kazee) during his tour, and they arrange to have cybersex. However, Fiona is disappointed when Gus does not arrive.

Debbie (Emma Kenney) and Derek (Luca Oriel) continue their relationship, and they decide it is time to consummate their relationship that night. With Fiona's help, Debbie goes to a Planned Parenthood meeting to get birth control pills. However, Debbie is informed that the pills will not work for two days, so Derek must use a condom. Amanda (Nichole Sakura) returns, and Lip (Jeremy Allen White) reveals he had sex with Helene (Sasha Alexander), straining their relationship. Kevin (Steve Howey) has brought in his children to college, and their constant cries annoy the students. Kevin unwittingly sells synthetic marijuana to a handful of college students, which leads to one student, Joaquin (José Julián), jumping out a second story window.

At Patsy's, Ian (Cameron Monaghan) gets distracted and puts his hand on the grill, severely wounding himself. He is tended at home by Sammi (Emily Bergl), and he opens up about his experience in the army and having left his position. Later, Ian takes Mickey (Noel Fisher) to a baseball field where they had sex, and they have a tense fight, although Ian admits this was the best experience he had in a long time. Frank shares his feelings for Bianca to Veronica (Shanola Hampton), stating he does not want anything in return. Frank visits her again, but Bianca's sister refuses to let him inside. He calls her from her window, saying he can help her in her struggle despite not having much to offer.

Lip takes Joaquin to Helene, asking her for help. She calls an ambulance, but tells Lip that he needs to prioritize responsibilities and act up. Afterwards, Lip kicks Kevin out of the dorm room, returning with Veronica. Debbie and Derek have sex, but Debbie advises him not to use a condom. Fiona meets with Sean (Dermot Mulroney), who bids farewell to his family. Ignoring Gus's calls, Fiona goes with Sean to a bar, where he gets into a fight with another man. Later, Fiona and Sean finally kiss. Bianca reveals to Frank that she chose not to get chemotherapy, and Frank promises to not get the treatment for her. Ian and Mickey return home, planning to have their first official date as couple. However, when they arrive, they discover that Sammi has called in army officials to inform them of Ian's desertion. Ian is arrested and taken away, just as Fiona arrives, and Sammi proclaims this is retaliation for Chuckie's imprisonment.

The episode was written by supervising producer Sheila Callaghan and directed by Michael Uppendahl. It was Callaghan's sixth writing credit, and Uppendahl's first directing credit.