Spertiniite is a rare copper hydroxide mineral. Chemically, it is copper(II) hydroxide with the formula Cu(OH)₂. It occurs as blue to blue-green tabular orthorhombic crystal aggregates in a secondary alkaline environment altering chalcocite. Associated minerals include chalcocite, atacamite, native copper, diopside, grossular, and vesuvianite.

It was first described in 1981 for an occurrence in the Jeffrey Mine of the Johns-Manville mine, Val-des-Sources, Quebec. It was named for mine geologist Francesco Spertini (born 1937). In addition to the type locality, it has also been reported from Mont Saint-Hilaire, Quebec; Ely, White Pine County, Nevada; and Bisbee, Cochise County, Arizona. It has been reported from Dzhezkazgan, Kazakhstan; from slag at Juliushutte, Astfeld, Harz Mountains, Germany; and from Tsumeb, Namibia.

A 2006 study has produced evidence the blue mineral chrysocolla may be a microscopic mixture of spertiniite, amorphous silica and water.