Suzi Ruffell (born 18 January 1986) is a British comedian, writer, and actress.

Ruffell was born in Portsmouth to a working-class family. Her father buys and sells lorries and her mother became his assistant after raising Suzi and her older brother.

Ruffell joined a youth drama group which had a major impact on her eventual career choice. She considered Victoria Wood, Catherine Tate, Dawn French and Jennifer Saunders to be her heroes. After Chichester College, she attended drama school at the Academy of Live and Recorded Arts in London, where she first performed stand-up. Ruffell was the first in her family to attend university.

Ruffell began her stand-up comedy career in November 2008 and has been performing stand-up full time since 2012.

Before she began touring as a solo performer, Ruffell had supported Alan Carr, Kevin Bridges, Josh Widdicombe, Joe Lycett, Romesh Ranganathan, and Katherine Ryan on national tours.

Ruffell's stand-up comedy tours include Social Chameleon (toured in 2014–2015), Common (2016–2017), Keeping It Classy (2018, her first headlining tour), Nocturnal (2019), and Dance Like Everyone's Watching (2019–2020). After a year and a half hiatus due to the COVID-19 pandemic, Ruffell resumed the Dance Like Everyone's Watching tour in autumn 2021.

Keeping it Classy was recorded for Live from the BBC and aired on 11 July 2018.

In 2017, Ruffell and her friend Tom Allen performed across the UK on a double-bill tour titled Hit the Road!