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THJ-2201

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THJ-2201

THJ-2201 is an indazole-based synthetic cannabinoid that presumably acts as a potent agonist of the CB1 receptor and has been sold online as a designer drug.

It is a structural analog of AM-2201 in which the central indole ring has been replaced by indazole.

THJ-2201 acts as a full agonist with a binding affinity of 1.34 nM at CB1 and 1.32 nM at CB2 cannabinoid receptors.

THJ-2201 has been linked to at least one hospitalization and death due to its use.

It is classified as a Schedule I controlled substance in the United States.

It is also an Anlage II controlled drug in Germany.

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