Talluza (Arabic: طلوزة) is a Palestinian village in the Nablus Governorate in the northern West Bank, located northeast of Nablus. According to the Palestinian Central Bureau of Statistics (PCBS) census, it had a population of 2,375 in 2007 and 2,795 in 2017.

Talluza is located 6.51 kilometers (4.05 mi) north of Nablus. It is bordered by al-Badhan and Wadi al Far'a to the east, Yasid to the north, and ‘Asira ash Shamaliya to the west and south.

Talluza may be identified with the Samaritan town of "Tur-Luzeh" (Tûr Lôzah), which according to Albright, is Aramaic for "almond mountain".

Pottery sherds from the Iron Age II and the Byzantine eras have been found here.

Robinson and Guérin suggested identifying Talluza with the ancient Canaanite and Israelite city of Tirzah, however, most scholars today identify Tirzah with the site of Tell el-Far'ah (North), 5 km to the ENE.

Talluza may be identified with Tira Luzeh where the High Priest Baba Rabba erected a synagogue in the 4th century CE. The Jerusalem Talmud mentions the village as "Turluzeh" where the Romans burnt the sacred Hebrew scrolls. In 1941, a Greek inscription was found bearing the name of "Yosef Ben Ya'akov Zechariah", a Samaritan from the 4th–5th centuries. Later, in 1985 a rock-hewn Samaritan burial cave containing three coffins for members of the Samaritan Ptolemayos family was excavated. A handful of glass beads and an oil lamp were also found in the excavation.

A columbarium and Byzantine-period ceramics have been found in the village. Pottery remains have also been found from the early Islamic and medieval periods. Inside the village is the maqam ("holy tomb") of Nabi Harun ("the Prophet Aaron") according to local tradition. North of the village is the shrine of Nabi Yahuda, consisting of relatively new buildings constructed on ancient foundations, that may be derived from the biblical name Ishud.

In 1322, the village was mentioned by Sir John Maundeville under the name of Deluze.