The Brothers Rico is a 1957 American crime film noir directed by Phil Karlson and starring Richard Conte, Dianne Foster and Kathryn Grant.

Eddie Rico (Richard Conte) is the happily married owner of a prosperous laundry company in Bayshore, Florida. Later in the film we discover that years ago he had been the accountant for a major crime syndicate. He has given up his ties to the syndicate, and hopes to adopt a child with his wife, Alice (Dianne Foster). When the film opens, Eddie's sleep is interrupted by a call from Phil, a mob operative, who demands Eddie provide employment and a place to lie low for someone who turns out to be a hitman named Wesson (William Phipps). Alice becomes worried that the syndicate will bring Eddie back into a life of crime. Eddie calms her, but then receives a worrisome letter from his mother saying that his two brothers, Johnny (James Darren) and Gino (Paul Picerni), who are both still involved with the mob, have disappeared.

Shortly thereafter, while he is driving, Eddie realizes the vehicle that taps him at a stop light is being driven by his brother, Gino. Off the main street, they both pull over; Gino slides into Eddie's front seat and, in desperation, begs Eddie to help him get out of the country. Gino admits to being the gunman in a gang killing and identifies Johnny as having been his driver. Gino now believes the syndicate is planning to get rid of him; out of the blue they've ordered him to St. Louis. Eddie cannot believe that the syndicate is after him; he has complete faith in the benevolence of Sid Kubik (Larry Gates), the syndicate boss, who Eddie believes thinks of the Ricos as family, just as Eddie thinks of Kubik as a father. Consequently, Eddie tells Gino to go to St. Louis—"Have I ever steered you wrong?"—and gives him some money to do so. When Eddie returns to work, he takes a call from "Uncle" Sid Kubik, who orders him to Miami for a face-to-face conference. Eddie leaves, despite his wife's objections that he will miss an adoption interview.

Eddie meets Kubik in Miami, where Kubik apologizes for the orders given earlier regarding Wesson and congratulates Eddie on his impending adoption. Kubik says the syndicate does not know where Johnny is, but they are concerned. It seems that Johnny's new wife's brother Peter Malaks (Lamont Johnson)—who doesn't at all approve of Johnny or of his having married his sister Norah—has met with prosecutors on a number of occasions. Naturally, the bosses feel that as a result of what Peter tells them, Johnny will be "persuaded" to turn on the syndicate and testify against them in return for clemency. After Eddie insists that he does not believe Johnny would ever rat on them, Kubik tells Eddie that while he believes in Johnny's loyalty, others aren't so sure. In order for Johnny's life to be saved, Kubik says that Eddie must find him and get him to leave the country. After Eddie leaves to do what he has been ordered, Kubik walks down the hall to enter another room where Gino, his face battered from a beating being administered by one of Kubik's henchmen, is seen slumped in a chair with only enough strength to raise his head and say with bitter sarcasm, "Thanks, uncle Sid."

Eddie arrives in New York City and finds Peter Malaks. When Eddie says that Johnny may be in a lot of trouble, Malaks angrily refuses to help find him, calling Johnny a gangster and telling Eddie that maybe Johnny would be better off dead. Eddie then visits his mother (Argentina Brunetti) to ask her where Johnny is, but she proclaims that even though she once took a bullet to protect Kubik's life, she no longer trusts the man, in large part because Gino had told her not to. Indeed, she tells Eddie as he is leaving not to trust anybody. When Eddie tells her that Johnny's life is in danger, she laments, kneeling to pray in front of a statue of the Virgin Mary she has sitting on a shelf, but refuses to tell Eddie anything. Finally, as Eddie is walking out the door, she relents and reveals, with great trepidation, that Johnny last wrote her from El Camino, California.

Eddie has to take two planes to El Camino, where he finds Johnny and his pregnant wife, Norah (Kathryn Grant) hiding out on a friend's farm. Johnny says he's left the syndicate because he wants his son to grow up to be clean and not know a life of crime. Norah, pregnant, is distraught at the prospect of Johnny being dragged back into the syndicate and collapses; she needs a doctor and one is called. Johnny tells Eddie to leave.

Eddie returns to his hotel where Mike Lamotta (Harry Bellaver), a local crime boss, is waiting in Eddie's room. There, Eddie realizes that Kubik has used him to locate Johnny and all along has intended that Johnny be killed. Lamotta orders Eddie to call Johnny and tell him to meet the mobsters waiting outside the house where he's staying. Instead, after Johnny joyously tells Eddie that he's a new father, Eddie urges Johnny to go to the cops; he is immediately knocked out by Lamotta's assistant, Gonzales (Rudy Bond). To save his wife and newborn son, Johnny goes outside, where he is killed.

As Eddie and Gonzales fly back to Florida, Eddie learns that Gino had attempted to flee the country and was also killed. While in a bathroom during their stopover in Phoenix, Eddie knocks Gonzales out. He takes Gonzales' pistol and calls Alice, telling her to leave their house in Florida and meet him in New York at a special place only they know about. Eddie then manages to elude Kubik's minions by hitching a ride to New York in a truck transporting new cars.