The Da Vinci Code is a 2006 mystery thriller film directed by Ron Howard, written by Akiva Goldsman, and based on Dan Brown's 2003 novel of the same name. The first in the Robert Langdon film series, the film stars Tom Hanks, Audrey Tautou, Ian McKellen, Alfred Molina, Jürgen Prochnow, Jean Reno, and Paul Bettany.

In the film, Robert Langdon, a professor of religious symbology from Harvard University, is the prime suspect in the grisly and unusual murder of Louvre curator Jacques Saunière. On the body, the police find a disconcerting cipher and start an investigation. Langdon escapes with the assistance of police cryptologist Sophie Neveu, and they begin a quest for the legendary Holy Grail. Sir Leigh Teabing, a noted British Grail historian, tells them that the actual Holy Grail is explicitly encoded in Leonardo da Vinci's wall painting The Last Supper. Also searching for the Grail is a secret cabal within Opus Dei, an actual prelature of the Holy See, who wish to keep the true Grail a secret to prevent the destruction of Christianity.

The film, like the book, was considered controversial. It was met with especially harsh criticism by the Catholic Church for the accusation that it is behind a two-thousand-year-old cover-up concerning what the Holy Grail really is and the concept that Jesus Christ and Mary Magdalene were married, producing a daughter, as well as its treatment of the organizations Priory of Sion and Opus Dei. Many members urged the laity to boycott the film. In the book, Brown states that the Priory of Sion and "all descriptions of artwork, architecture, documents and secret rituals in this novel are accurate".

The Da Vinci Code premiered as the opening film of the 59th Cannes Film Festival on May 17, 2006, and was theatrically released in the United States on May 19. The film received generally negative reviews from critics, but was a commercial success, grossing $224 million in its worldwide opening weekend and an initial total of $760 million worldwide against a $125 million production budget, becoming the second-highest-grossing film of 2006, as well as Howard's highest-grossing film to date. It was followed by two sequels, both directed by Howard: Angels & Demons (2009) and Inferno (2016).

Louvre curator Jacques Saunière is pursued by Silas, an albino Catholic monk who demands the location of the "keystone" to find and destroy the Holy Grail. Saunière gives him a false lead and is murdered. The police find his body posed like Da Vinci's Vitruvian Man. Police captain Bezu Fache summons Robert Langdon, an American symbologist who is in Paris for a lecture on the interpretation of symbols, to examine Saunière's body.

Langdon is shown the body and a secret message, readable only by UV light. It contains an out-of-order Fibonacci sequence. Police cryptographer Sophie Neveu, Saunière's granddaughter, says that Fache planted a tracker on him after finding the words "P.S. Find Robert Langdon" at the end of Saunière's secret message. Fache believes that Langdon murdered Saunière. Sophie throws away the tracker, distracting the police while they sneak around the Louvre, finding more clues in Leonardo da Vinci's works. Langdon deduces that Saunière was the grand master of the Priory of Sion.

Silas works for an anonymous person referred to as "The Teacher", along with members of Opus Dei, led by Bishop Aringarosa. He travels to the church as directed by Saunière and finds a marker with "Job 38:11" inscribed in it, the bible verse that begins, "Here you shall come, and no farther..." Enraged, he kills the nun in residence.

Langdon and Sophie travel to a French bank to access Saunière's safe deposit box, using the Fibonacci sequence. Inside is a cryptex, a cylindrical container that contains a message on papyrus. It can only be opened without destroying the contents by turning dials to spell a code word. As the police arrive, bank manager Andre Vernet helps Langdon and Sophie escape, then attempts to steal the cryptex and murder them. Langdon and Sophie escape with it.