Etrigan the Demon is a superhero appearing in American comic books published by DC Comics. Created by Jack Kirby, Etrigan is a demon from Hell who, despite his violent tendencies, usually finds himself allied with the forces of good, mainly because of the alliance between the heroic characters of the DC Universe and Jason Blood, a human to whom Etrigan is bound. Etrigan is commonly depicted as a muscular humanoid creature with orange or yellow skin, horns, red eyes, and pointed, webbed ears, who frequently speaks in rhymes. The character was originally based in Gotham City, leading to numerous team-ups with Batman.

Since his conception, Etrigan has been adapted into several forms of media outside of comics, including animated series, films, and video games. He is voiced by Michael T. Weiss in the DC Animated Universe, Dee Bradley Baker in Batman: The Brave and the Bold, Patrick Seitz in Justice League Action, and Ray Chase in the DC Animated Movie Universe.

Kirby's former assistant, Mark Evanier, said that Carmine Infantino asked Jack Kirby to create a new monster hero. Kirby or Infantino mentioned a demon, and Kirby from that point worked on creating a demonic character. Evanier said that he was with Kirby and several others during a dinner at a restaurant, and Kirby came up with Etrigan's name, back story, and motivations on the spot. Kirby intended to create the character but pass him off to others to write and draw. However, Infantino convinced him to make the first issue and made the decision final by suspending Kirby's unprofitable Fourth World comics series. Kirby then moved full-time to the Etrigan comics.

Etrigan first appeared in The Demon #1 (September 1972) and was created by Jack Kirby. He created him at the behest of DC, who saw it as likely to be more commercially successful than the Fourth World and cancelled New Gods and Forever People to facilitate work on the new title. According to Evanier, Kirby had no interest in horror comics, but created Etrigan in response to DC's demand for a horror character. Kirby was annoyed that Etrigan's popularity forced him to abandon the Fourth World titles before he was done with them.

Etrigan returned for a four-issue miniseries in 1987, written and illustrated by Matt Wagner. Alan Grant followed this with an Etrigan feature in Action Comics Weekly #636-641 and a second ongoing title in 1990. The 1990 series lasted 58 issues, two Annuals and one #0 issue. Garth Ennis took over the title beginning with issue #40. Ennis' run included the first appearance of his character Hitman. This series was followed by a miniseries, Driven Out. Following this, John Byrne's Blood of the Demon lasted 17 issues, and ignored much of the continuity that took place after Kirby's initial run.

While his first monthly comic book series was short-lived, and his second was canceled after five years, Etrigan remains a popular supporting character with occasional additional miniseries. Series in which Etrigan has appeared include Alan Moore's Swamp Thing, Neil Gaiman's The Sandman, Kevin Smith's Green Arrow and Batman: The Widening Gyre, Garth Ennis's Hitman, and Cosmic Odyssey by Jim Starlin and Mike Mignola.

In The New 52 rebooted continuity, DC Comics launched a new series featuring Etrigan titled Demon Knights, which debuted on September 14, 2011. It was written by Paul Cornell and drawn by Diógenes Neves.

Etrigan will receive a new ongoing series in March 2026 as part of the "DC Next Level" publishing initiative.