The Looney Tunes Show is an American animated sitcom produced by Warner Bros. Animation, developed by Sam Register, Spike Brandt and Tony Cervone, and broadcast on Cartoon Network for two seasons from May 3, 2011, to August 27, 2013. (An episode skipped in the U.S. was later broadcast on August 31, 2014, after it had been first broadcast overseas in proper sequence.) The series featured characters from the Looney Tunes and Merrie Melodies theatrical cartoon shorts in a sitcom format with Bugs Bunny and Daffy Duck, who live a suburban life together within a neighborhood of fellow cartoon neighbors, dealing with various issues in their own way. Many episodes also include a musical short under the Merrie Melodies name, and the first season also includes computer-animated shorts involving new antics between Wile E. Coyote and the Road Runner.

The series received mixed reviews from critics, who praised the visual style and voice acting, but heavily criticized its lack of originality and departures from the source material. In later years, the series has gained a cult following.

The Looney Tunes Show revolves around the lives of Bugs Bunny, who owns a suburban home after inventing carrot peelers that pay him royalties, and Daffy Duck, who is Bugs' roommate, as they deal with different issues and problems that they encounter, some of the time caused by Daffy's rather bad lifestyle. The pair reside within a neighborhood inhabited by a number of notable Looney Tunes characters including Yosemite Sam, Granny, Gossamer, and Speedy Gonzales, with both Bugs and Daffy having girlfriends in the form of Lola Bunny and Tina Russo, and a regular friendship with Porky Pig. Other Looney Tunes characters, like Elmer Fudd, Foghorn Leghorn, and Sylvester and Tweety, have less prominent roles but still partake in stories in their own way.

Unlike other Looney Tunes productions, the series focused less on slapstick and fewer visual gags, in favor of sitcom elements including love triangles, employment and rooming. Episodes often contained at least two stories featuring Bugs and Daffy, and sometimes led by others in the show.

Alongside the main plots of the episode, the story would often include Merrie Melodies – two-to-four-minute music videos showcasing classic characters singing brand new original songs. For the first season only, the show also included new computer-animated shorts involving Wile E. Coyote and the Road Runner, and a new spate of antics between them.

The Looney Tunes Show was originally envisioned as Looney Tunes Laff Riot, a "true-to-the-classics" show emulating the original run of Looney Tunes shorts announced in July 2009 by Warner Bros. Animation. However, it was scrapped because the executives were not impressed, and it was later retooled into the sitcom-inspired The Looney Tunes Show which premiered on May 3, 2011, on Cartoon Network. The show features new character designs by Ottawa-based artist Jessica Borutski which were first created for Looney Tunes Laff Riot and also later retooled for the final series. The Laff Riot pilot would surface on September 4, 2020.

As is standard for most modern animated sitcoms like The Simpsons and Family Guy, the series does not use a laugh track.

The animation was produced by Yearim and Rough Draft Korea, along with Toon City Animation in the first season. The Wile E. Coyote and the Road Runner shorts were produced by Crew972.