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Thomas Burr Osborne (chemist)
Thomas Burr Osborne (August 5, 1859 – January 29, 1929) was an American biochemist who, with Lafayette Mendel, independently discovered Vitamin A, though Elmer McCollum and Marguerite Davis were ultimately given credit, as they had submitted their paper first by three weeks. He is known for his work isolating and characterizing seed proteins, and for determining protein nutritional requirements. His career was spent at the Connecticut Agricultural Experiment Station.
Thomas Burr Osborne was born in New Haven, Connecticut on August 5, 1859. He was the son of lawyer Arthur Dimon Osborne and the grandson of US Representative Thomas Burr Osborne. He earned an undergraduate degree from Yale College in 1881, and a PhD in chemistry there in 1885.
He married Elizabeth Annah Johnson on June 23, 1886, and they had one son.
Osborne died at his home in New Haven on January 29, 1929.
His life exhibited "a single purpose, the understanding of the relationships of proteins to each other and the animal world. He began his researches upon vegetable proteins in 1888,..." He published his findings in The Vegetable Proteins in 1909.
Osborne realized the polypeptide structure of proteins: "The nature of proteins in seeds was greatly elucidated in the opening years of the 20th century by T.B. Osborne, who developed methods for their isolation and purification, by means of which he discovered the chemical differences in proteins of various plants. His work revealed an imposing number of vegetable proteins. Osborne considered that the amino acids are for the most part united in the protein molecule in polypeptide union; that is, by the union of the NH2 of one amino acid with the carboxyl group of another."
The American chemist Thomas B. Osborne was (viewed retropectively) head and shoulders above most of his contemporaries: compulsive attention to meticulous purification, reproducibility, error analysis, etc. shine through all his work. Although most of his work was carried out on seed proteins ... his results had far-reaching significance.
Osborne wrote over 100 papers with longtime collaborator Lafayette Mendel. Both were appointees of the Connecticut Agricultural Experiment Station. In their early work, they studied the deadly poison ricin which is classified as a type 2 ribosome inactivating protein (RIP) from castor beans.
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Thomas Burr Osborne (chemist)
Thomas Burr Osborne (August 5, 1859 – January 29, 1929) was an American biochemist who, with Lafayette Mendel, independently discovered Vitamin A, though Elmer McCollum and Marguerite Davis were ultimately given credit, as they had submitted their paper first by three weeks. He is known for his work isolating and characterizing seed proteins, and for determining protein nutritional requirements. His career was spent at the Connecticut Agricultural Experiment Station.
Thomas Burr Osborne was born in New Haven, Connecticut on August 5, 1859. He was the son of lawyer Arthur Dimon Osborne and the grandson of US Representative Thomas Burr Osborne. He earned an undergraduate degree from Yale College in 1881, and a PhD in chemistry there in 1885.
He married Elizabeth Annah Johnson on June 23, 1886, and they had one son.
Osborne died at his home in New Haven on January 29, 1929.
His life exhibited "a single purpose, the understanding of the relationships of proteins to each other and the animal world. He began his researches upon vegetable proteins in 1888,..." He published his findings in The Vegetable Proteins in 1909.
Osborne realized the polypeptide structure of proteins: "The nature of proteins in seeds was greatly elucidated in the opening years of the 20th century by T.B. Osborne, who developed methods for their isolation and purification, by means of which he discovered the chemical differences in proteins of various plants. His work revealed an imposing number of vegetable proteins. Osborne considered that the amino acids are for the most part united in the protein molecule in polypeptide union; that is, by the union of the NH2 of one amino acid with the carboxyl group of another."
The American chemist Thomas B. Osborne was (viewed retropectively) head and shoulders above most of his contemporaries: compulsive attention to meticulous purification, reproducibility, error analysis, etc. shine through all his work. Although most of his work was carried out on seed proteins ... his results had far-reaching significance.
Osborne wrote over 100 papers with longtime collaborator Lafayette Mendel. Both were appointees of the Connecticut Agricultural Experiment Station. In their early work, they studied the deadly poison ricin which is classified as a type 2 ribosome inactivating protein (RIP) from castor beans.