Todd Huffman is an American technology entrepreneur, transhumanist and photographer. He was co-founder of the biomedical imaging company 3Scan, member of the disaster aid group Synergy Strike Force, signals intelligence researcher for DARPA, and co-founder of the "unconference" BIL Conference.

He obtained a B.S. in Neuroscience in 2003 from California State University, Long Beach, and an M.S. in Computational Biosciences at Arizona State University in 2006.

While attending college at California State University, Long Beach (CSULB), Huffman became interested in cryopreservation, the process of cryogenically preserving brains with the intent of reviving it in the future once the technology becomes available, after reading about the subject on the Extropy Institute's mailing list. After networking with clients of the cryonics service provider Alcor Life Extension Foundation that he met through an Extropian conference, Huffman signed up for the service in 2002.

After graduating from CSULB in 2003, Huffman joined Alcor full-time as a researcher and a field recovery technician preparing brains for preservation at the site of death. After starting graduate school Huffman left his full-time position at Alcor, but continued to consult for the organization as well as another cryonics company, Suspended Animation, Inc.

Huffman has a tattoo on his torso with instructions for how to prepare his body for freezing in the event of his death.

In 2008, Huffman co-founded of the BIL Conference, an "unconference" organized and observed by the participants as an unaffiliated counterpart to TED’s structured, ‘invite-only’ paid conference.

Huffman has served as a board member for the Timothy Leary Archives.

In January 2009, Huffman was elected to the board of directors of Humanity+, an organization dedicated to the promotion of transhumanism, an ideology that promotes enhance longevity, cognition, physical performance, and well-being of humans through technology.