"Trinity War" is an 11-issue comic book story arc first published in 2013 by DC Comics, featuring the fictional superhero teams the Justice League, Justice League of America, and Justice League Dark. The arc spans several titles, including Justice League, Justice League of America, Justice League Dark, Constantine, Trinity of Sin: Pandora and Trinity of Sin: The Phantom Stranger. The story is an action-mystery that sees the Justice League, Justice League of America, and Justice League Dark clash, in order to solve the mystery of Pandora's Box. The event also introduces the Crime Syndicate and the reveal of Earth-3 to The New 52.

The main storyline received generally positive reviews, though it was criticized for not having a true conclusion, instead leading directly into the "Forever Evil" storyline; the tie-in titles received mixed reviews. Every title involved in the story was collected into a trade paperback entitled Justice League: Trinity War.

Pandora appeared in all first issues of the First and Second Wave titles of The New 52. Many of the stories since The New 52 was created at the end of Flashpoint lead up to "Trinity War". Some of these stories and events include:

In the year 8000 BC, Pandora finds the box and inadvertently opens it, unleashing the Seven Sins on the world. As a result, she is punished by the Council of Wizards with immortality. Pandora begins her travels, training and trying to destroy the Seven Sins. In the present, she receives information from the Wizard informing her that the box can only be opened by either the purest or darkest of heart. Pandora approaches Superman to open her box, believing he is 'without sin', but when he touches the box he appears to become possessed. Pandora manages to escape with the box, after which Superman seems to return to normal.

Shazam, having defeated his arch-enemy Black Adam, journeys to Kahndaq to bury him, inadvertently risking a diplomatic incident. Superman and the Justice League attempt to stop Shazam, which escalates into a fight. Amanda Waller decides it is the perfect opportunity for the Justice League of America to confront the Justice League, and dispatches them. During the conflict, it appears as though Superman murders the JLA's newest recruit Doctor Light. Seeming to have lost control of his powers, Superman surrenders himself to A.R.G.U.S.

Wonder Woman, believing that Pandora's box is responsible for Superman's actions, meets with Hephaestus, for answers about the box. She learns that he did not forge it and that Zeus and the other gods used Pandora to open the box because it contained something that the Gods of Olympus could not control. She meets with Justice League Dark to recruit them to track down Pandora. At A.R.G.U.S. headquarters, the Question enters Superman's cell and releases him.

The Question explains that he has evidence that indicates Doctor Psycho was in Kahndaq when Doctor Light was killed. Superman is physically ill and struggles to control his powers as he and the Question break out of the base to track down Psycho, with several other heroes in tow. When they confront Psycho, they determine that although he was present, he was not responsible for what happened in Kahndaq. Meanwhile, Pandora attempts to convince Vandal Savage to open the box, but he is also unable to do so.

While Batman examines Doctor Light's body, the Phantom Stranger arrives to warn him that should Wonder Woman locate Pandora and the box, it will be the death of all. They confront Wonder Woman and the Justice League Dark at Constantine's House of Mystery, but when Wonder Woman questions the Phantom Stranger about Superman's ailment, the Stranger admits he does not know what caused Superman's condition.