Tyson Gamble (born 21 June 1996) is an Australian professional rugby league footballer who plays as five-eighth and halfback for the Newcastle Knights in the National Rugby League.

He previously played for the Wests Tigers and Brisbane Broncos in the NRL.

Gamble was born in Brisbane, Queensland, Australia. Gamble played his junior football at Albany Creek and moved to the Redcliffe Dolphins at age 16.

In 2016, when Gamble played in the Redcliffe Dolphins’ Brisbane Rugby League team, he won the Don McLennan Trophy for best player in the grand final. Gamble progressed through to the grades to play for the Redcliffe Dolphins senior side in the Queensland Cup. In May 2017, he signed a 2-year contract with the Wests Tigers starting in 2018.

Gamble started the season playing for the Wests Tigers Intrust Super Premiership NSW team, Western Suburbs. He played a part in the Magpies’ early successes that year – scoring a try in Round 1, and playing a leading role in his team's consecutive wins early in the year.

In round 15 of the 2018 NRL season, he made his NRL debut for the Wests Tigers against the Canberra Raiders, but it was his only appearance for the season.

On 6 May, Gamble was selected for the Canterbury Cup NSW residents side to play against the Queensland residents representative team.

On 25 June, it was announced that Gamble had been released from the Wests Tigers, effective immediate, to return to Queensland.