United Productions of America, better known as UPA, was an American animation studio and later distribution company founded in 1941 as Industrial Film and Poster Service by former Walt Disney Productions employees. Beginning with industrial and World War II training films, UPA eventually produced theatrical shorts for Columbia Pictures such as the Mr. Magoo series. In 1956, UPA produced a television series for CBS, The Gerald McBoing-Boing Show, hosted by Gerald McBoing Boing. In the 1960s, UPA produced syndicated Mr. Magoo and Dick Tracy television series and other series and specials, including Mister Magoo's Christmas Carol. UPA also produced two animated features, 1001 Arabian Nights and Gay Purr-ee, and distributed Japanese films from Toho Studios in the 1970s and 1980s.

Universal Pictures currently owns the majority of the UPA library after their acquisition of DreamWorks Animation in 2016. The theatrical shorts, which were released by Columbia Pictures, are still owned by that studio (via parent company Sony Pictures Entertainment).

UPA was founded in the wake of the Disney animators' strike of 1941, which resulted in the exodus of a number of long-time Walt Disney Animation Studios staff members. Among them was John Hubley, a layout artist who was unhappy with the ultra-realistic style of animation that Disney had been utilizing. Along with a number of his colleagues, Hubley believed that animation did not have to be a painstakingly realistic imitation of real life; they felt that the medium of animation had been constrained by efforts to depict cinematic reality. Chuck Jones' 1942 cartoon The Dover Boys had demonstrated that animation could freely experiment with character design, depth, and perspective to create a stylized artistic vision appropriate to the subject matter. Hubley, Bobe Cannon, and others at UPA, sought to produce animated films with sufficient freedom to express design ideas considered radical by other established studios.

In 1941, Zack Schwartz, David Hilberman, and Stephen Bosustow formed a studio called first Industrial Film and Poster Service, where they were free to apply their new techniques in film animation. Finding work (and income) in the then-booming field of wartime work for the government, the small studio produced a cartoon sponsored by the United Auto Workers (UAW) in 1944. Hell-Bent for Election was directed by Chuck Jones and was produced for the reelection campaign of FDR. The film was a success, and it led to another assignment from the UAW, Brotherhood of Man (1945). The film, directed by Bobe Cannon, advocated tolerance of all people. The short was innovative not only in its message but in its very flat, stylized design, in complete defiance of the Disney approach. With its new-found status, the studio renamed itself United Productions of America (UPA).

Initially, UPA contracted with the United States government to produce its animation output, but the government contracts began to evaporate as the FBI began investigating Communist activities in Hollywood in the late 1940s. No formal charges were filed against anyone at UPA in the beginnings of McCarthyism, but the government contracts were lost as Washington severed its ties with Hollywood.

UPA entered the crowded field of theatrical cartoons to sustain itself and gained a contract with Columbia Pictures. Columbia had historically been an also-ran in the field of animated shorts, and it was not satisfied with the output of its Screen Gems cartoon studio. The UPA animators applied their stylistic concepts and storytelling to Columbia's characters The Fox and the Crow with the shorts Robin Hoodlum (1948) and The Magic Fluke (1949), both directed by Hubley. Both were nominated for Academy Awards, and Columbia granted the studio permission to create its own new characters. UPA responded, not with another "funny animal", but a star that was a human character, a crotchety, nearsighted old man. The Ragtime Bear (1949), the first appearance of Mr. Magoo, was a box-office hit, and UPA's star quickly rose as the 1950s dawned.

With a unique, sparse drawing style that contrasted greatly with other cartoons of the day, not to mention the novelty of a human character in a field crowded with talking cats, mice, and rabbits, the Mr. Magoo series won accolades for UPA. Two Magoo cartoons won the Academy Award for Best Short Subject (Cartoons): When Magoo Flew (1954) and Magoo's Puddle Jumper (1956).

UPA scored another hit with Gerald McBoing-Boing (1950), based on a record by Dr. Seuss. Gerald McBoing-Boing won UPA the Academy Award in 1950; UPA cartoons would receive a total of fifteen Oscar nominations between 1949 and 1959. In December 1950, UPA announced plans for a feature-length film based on the work of cartoonist and humorist James Thurber. The film was to combine live action and animation and was tentatively titled Men, Women and Dogs, but it was never completed. (Only one of the Thurber pieces intended for this feature, The Unicorn in the Garden, was eventually released as a short subject.) Shorts such as The Tell-Tale Heart and Rooty Toot Toot featured striking, sophisticated designs unlike anything offered by competing studios. The "UPA style" began to influence significant changes at the other major animation studios, including Warner Bros., MGM, Famous Studios, and even Disney, ushering in a new era of experimentation in animation.