USS Indiana was the lead ship of her class and the first battleship in the United States Navy comparable to foreign battleships of the time. Authorized in 1890 and commissioned five years later, she was a small battleship, though with heavy armor and ordnance. The ship also pioneered the use of an intermediate battery. She was designed for coastal defense and as a result, her decks were not safe from high waves on the open ocean.

Indiana served in the Spanish–American War (1898) as part of the North Atlantic Squadron. She took part in both the blockade of Santiago de Cuba and the Battle of Santiago de Cuba, which occurred when the Spanish fleet attempted to break through the blockade. Although unable to join the chase of the escaping Spanish cruisers, she was partly responsible for the destruction of the Spanish destroyers Plutón and Furor. After the war, she quickly became obsolete—despite several modernizations—and spent most of her time in commission as a training ship or in the reserve fleet, with her last commission during World War I as a training ship for gun crews. She was decommissioned for the third and final time in January 1919 and was shortly after reclassified Coast Battleship Number 1 so that the name Indiana could be reused. She was sunk in shallow water as a target in aerial bombing tests in 1920, and her hull was sold for scrap in 1924.

Indiana was constructed from a modified version of a design drawn up by a US Navy policy board in 1889 for a short-range battleship. The original design was part of an ambitious naval construction plan to build 33 battleships and 167 smaller ships. The United States Congress saw the plan as an attempt to end the U.S. policy of isolationism and did not approve it, but a year later, the United States House of Representatives approved funding for three coast defense battleships, which would become Indiana and her sister ships Massachusetts and Oregon. The "coast defense" designation was reflected in Indiana's moderate endurance, relatively small displacement and low freeboard, which limited seagoing capability. The ships proved to be disappointments in service, as they were badly overweight upon completion, their low freeboard hampered operations at sea, and they handled poorly. Conway's All the World's Fighting Ships describes her design as "attempting too much on a very limited displacement." They were nevertheless the first modern battleships for the American fleet.

Indiana was 351 feet 2 inches (107.04 m) long overall and had a beam of 69 ft 3 in (21.11 m) and a draft of 24 ft (7.3 m). She displaced 10,288 long tons (10,453 t) as designed and up to 11,688 long tons (11,876 t) at full load. The ship was powered by two-shaft triple-expansion steam engines rated at 9,000 indicated horsepower (6,700 kW) and four coal-fired fire-tube boilers, generating a top speed of 15 knots (28 km/h; 17 mph). She had a cruising radius of 5,640 nautical miles (10,450 km; 6,490 mi) at a speed of 10 knots (19 km/h; 12 mph). As built, she was fitted with a heavy military mast, which was later supplemented by a stern cage mast in 1910–1911. She had a crew of 32 officers and 441 enlisted men, which increased to a total of 586–636 officers and enlisted.

The ship was armed with a main battery of four 13 in (330 mm) /35 caliber guns in two twin gun turrets on the centerline, one forward and aft. The secondary battery consisted of eight 8-inch (203 mm) /35 cal. guns, which were placed in four twin wing turrets. These were supported by a battery of six 6 in (150 mm) /40 cal. guns in a casemate battery amidships. For close-range defense against torpedo boats, she carried twenty 6-pounder guns and six 1-pounder guns in individual mounts. As was standard for capital ships of the period, Indiana carried 18 in (457 mm) torpedo tubes in above-water mounts, though the number is unclear. According to Conway's, she was fitted with six tubes, though the naval historian Norman Friedman states she was ordered with seven but completed with five.

Indiana's main armored belt was 18 in (457 mm) thick over the magazines and the machinery spaces and was reduced to 4 in (102 mm) at the bow and stern. The main battery gun turrets had 17-inch (432 mm) thick sides, and the supporting barbettes had the same thickness of armor plate on their exposed sides. The 8 in turrets had 6 in of armor plating, and the casemate battery had 5 in (127 mm). The conning tower had 10 in (254 mm) thick sides.

Construction of the ships was authorized on 30 June 1890, and the contract for Indiana—not including guns and armor—was awarded to William Cramp & Sons in Philadelphia, who offered to build it for $3,020,000. The ship's total cost was almost twice as high, approximately $6,000,000. The contract specified the ship had to be built in three years, but slow delivery of armor plates caused a two-year delay. Indiana's keel was laid down on 7 May 1891 and she was launched on 28 February 1893, attended by around 10,000 people, including President Benjamin Harrison, several members of his cabinet and the two senators from Indiana. During her fitting-out in early March 1894, the ship undertook a preliminary sea trial to test her speed and machinery. At this point, her side armor, guns, turrets, and conning tower had not yet been fitted, and her official trials would not take place until October 1895 due to the delays in armor deliveries.

Indiana was commissioned on 20 November 1895 under the command of Captain Robley D. Evans. After further trials, the ship joined the North Atlantic Squadron under the command of Rear Admiral Francis M. Bunce, which conducted training exercises along the East Coast of the United States. In late 1896, both main turrets broke loose from their clamps in heavy seas. Because the turrets were not centrally balanced, they swung from side to side with the ship's motion, until they were secured with heavy ropes. Heavier clamps were installed, but in February 1896, while conducting fleet maneuvers with the North Atlantic squadron, the Indiana encountered more bad weather and started rolling heavily. Her new captain, Henry Clay Taylor, promptly ordered her back to port for fear the clamps would break again. This convinced the navy that bilge keels—omitted during construction because, with them, the ship could not fit in most American dry docks—were necessary to reduce the rolling, and they were installed on all three ships of the Indiana-class.